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Occupational exposure to formaldehyde: effects of years of exposure in the frequency of micronucleus

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Formaldehyde: an important industrial compound used in the manufacture of synthetic resins and chemical compounds such as lubricants and adhesives; also applied as a disinfectant, preservative and in cosmetics productions; relevant workplace exposure to FA also occurs in anatomy, pathology and in mortuaries; classified by IARC as carcinogenic to humans (Group 1), based on sufficient evidence in humans and experimental animals; manifold in vitro studies indicated that FA can induce genotoxic effects in proliferating cultured mammalian cells. Aim of the study: to evaluate if years of exposure induced a genotoxic biomarkers increase, namely MN in lymphocytes and buccal cells, in workers occupationally exposed to FA (factory and pathology anatomy laboratory).

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Anatomia patológica Saúde ocupacional Formaldeído Factor de risco

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Ladeira C, Viegas S, Nunes C, Malta-Vacas J, Gomes M, Mendonça P, Prista J, Gomes MC, Brito M. Occupational exposure to formaldehyde: effects of years of exposure in the frequency of micronucleus. In 8th International Symposium on Biological Monitoring in Occupational and Environmental Health, Finland, 6th September 2010. Oral presentation.

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