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A method for estimating gestational age of fetal remains based on long bone lengths

2016-09Journal article Restricted access
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dc.contributor.authorCarneiro, Cristiana
dc.contributor.authorCurate, Francisco
dc.contributor.authorCunha, Eugénia
dc.date.accessioned2016-12-21T17:16:38Z
dc.date.available2016-12-21T17:16:38Z
dc.date.issued2016-09
dc.description.abstractThe estimation of gestational age (GA) in fetal human remains is important in forensic settings, particularly to assess fetal viability, in addition to often being the only biological profile parameter that can be assessed with some accuracy for non-adults. The length of long bone diaphysis is one of the most frequently used methods for fetal age estimation. The main objective of this study was to present a simple and objective method for estimating GA based on the measurements of the diaphysis of the femur, tibia, fibula, humerus, ulna, and radius. Conventional least squares regression equations (classical and inverse calibration approaches) and quick reference tables were generated. A supplementary objective was to compare the performance of the new formulae against previously published models. The sample comprised 257 fetuses (136 females and 121 males) with known GA (between 12 and 40 weeks) and was selected based on clinical and pathological information. All measurements were performed on radiographic images acquired in anonymous clinical autopsy records from spontaneous and therapeutic abortions in two Portuguese hospitals. The proposed technique is straightforward and reproducible. The models for the GA estimation are exceedingly accurate and unbiased. Comparisons between inverse and classical calibration show that both perform exceptionally well, with high accuracy and low bias. Also, the newly developed equations generally outperform earlier methods of GA estimation in forensic contexts. Quick reference tables for each long bone are now available. The obtained models for the estimation of gestational age are of great applicability in forensic contexts.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCarneiro C, Curate F, Cunha E. A method for estimating gestational age of fetal remains based on long bone lengths. Int J Legal Med. 2016;130(5):1333-41.pt_PT
dc.identifier.doi10.1007/s00414-016-1393-5pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.21/6650
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringer Verlagpt_PT
dc.relation.publisherversionhttp://link.springer.com/article/10.1007%2Fs00414-016-1393-5pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectAge estimationpt_PT
dc.subjectFetuspt_PT
dc.subjectLong bonespt_PT
dc.subjectRadiographypt_PT
dc.subjectRegression equationspt_PT
dc.subjectLegal medicinept_PT
dc.titleA method for estimating gestational age of fetal remains based on long bone lengthspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage1341pt_PT
oaire.citation.issue5pt_PT
oaire.citation.startPage1333pt_PT
oaire.citation.titleInt J Legal Medpt_PT
oaire.citation.volume130pt_PT
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT

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