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Azole-resistance of Mucorales order in three occupational environments and potential health risks for workers

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Introduction: Mucorales can cause severe infections, such as mucormycoses, associated with a great deal of morbidity. The frequency and clinical importance of these infections are common, likely due to the increasing number of immunocompromised hosts in the last decades. Triazoles, including the newer posaconazole, are alternatives to first-line treatment for mucormycoses, with azole activity reported as species-dependent. The emergence of azole resistance in the environment, including occupational environments, is of concern, representing a risk for exposed workers. Here, we present the distribution and screening of azole resistance of two common species of Mucorales in the environment of three distinct occupational settings in Portugal.

Descrição

Project “Waste Workers’ Exposure to Bioburden in the Truck Cab during Waste Management - W2E Bioburden” (IPL/2016/W2E_ESTeSL).
Project “Occupational exposure of ambulance drivers to bioburden” (IPL/2020/BIO-AmbuDrivers_ESTeSL).
FCT_UIDB/05608/2020. FCT_UIDP/05608/2020.

Palavras-chave

Occupational health Occupational exposure Azole resistance Mucorales Portugal Project “Waste Workers’ Exposure to Bioburden in the Truck Cab during Waste Management - W2E Bioburden” IPL/2016/W2E_ESTeSL Project “Occupational exposure of ambulance drivers to bioburden” IPL/2020/BIO-AmbuDrivers_ESTeSL FCT_UIDB/05608/2020 FCT_UIDP/05608/2020

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Citação

Caetano LA, Gomes B, Dias M, Pena P, Cervantes R, Viegas C. Azole-resistance of Mucorales order in three occupational environments and potential health risks for workers. In: 10th Advances Against Aspergillosis and Mucormycosis [online], February 2-3, 2020. poster 60.

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