Repository logo
 
Publication

Comparison of body fat content and distribution of familial amyloidotic polyneuropathy patients versus healthy subjects

2009-05Conference object Open access
Simple item page
dc.contributor.authorPimenta, Nuno
dc.contributor.authorSanta-Clara, Helena
dc.contributor.authorTomás, Maria Teresa
dc.contributor.authorMonteiro, Estela
dc.contributor.authorCabri, Jan
dc.contributor.authorFreire, António
dc.contributor.authorBarroso, Eduardo
dc.contributor.authorSardinha, Luís
dc.contributor.authorFernhall, Bo
dc.date.accessioned2011-11-08T14:09:54Z
dc.date.available2011-11-08T14:09:54Z
dc.date.issued2009-05
dc.description.abstractThe deposition of amyloid fibers at the peripheral nervous system can induce motor neuropathy in Familial Amiloidotic Polyneuropethy (FAP) patients. This produces progressive reductions in functional capacity. The only treatment for FAP is a liver transplant, followed by aggressive medication that can affect patients' metabolism. To our knowledge, there are no data on body fat distribution or comparison between healthy and FAP subjects, which may be important for clinical assessment and management of this disease. PURPOSE: To analyze body fat content and distribution between FAP patients and healthy subjects. METHODS: Body fat content and distribution were measured through Double Energy X-ray Densitometry (DXA) in two groups. Group 1 consisted of 43 Familial Amyloidotic Polyneuropathy patients (19 males, 32 + 8 Yrs, and 24 females, 37 + 5 yrs), who had liver transplant less than 2 months before. Group 2 consisted of 18 healthy subjects of similar age (8 males, 36 + 7 yrs, and 10 females, 39 + 5 yrs). RESULTS: Healthy subjects showed higher values than FAP patients for: BMI (24,2+2,3kg/m2 vs 22,3+3,8 kg/m2 respectively, p<0,05), % trunk BF (26,21+8,34kg vs 20,78+9,05kg respectively, p<0,05), % visceral BF (24,43+7,97% vs 19,21+9,30% respectively, p<0,05), % abdominal BF (26,63+8,51% vs 20,63+10,35% respectively, p<0,05) abdominal subcutaneous BF (0,533+0,421kg vs 0,353+0,257kg respectively, p=0,05), abdominal BF/BF ratio (0,09+0,02 vs 0,08+0,02 respectively, p<0,05) and abdominal BF/trunk BF ratio (0,19+0,03 vs 0,17+0,03 respectively, p<0,05). CONCLUSIONS: These results showed that FAP patients soon after liver transplantation exhibited a healthier body fat profile compared to controls. However, fat content and distribution varied widely in FAP subjects, suggesting an individualized approach for assessment and intervention rather than general guidelines. Future research is needed to investigate the long term consequences on body fat following liver transplant in this population.por
dc.identifier.citationPimenta N, Santa-Clara H, Tomás MT, Monteiro E, Cabri J, Freire A, Barroso E, Sardinha L, Fernhall B. Comparison of body fat content and distribution of familial amyloidotic polyneuropathy patients versus healthy subjects. Med Sci Sports Exerc. 2009;41(5 Suppl 1):402.por
dc.identifier.issn1530-0315
dc.identifier.urihttp://hdl.handle.net/10400.21/277
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherLippincott Williams and Wilkinspor
dc.relation.publisherversionhttp://journals.lww.com/acsm-msse/Citation/2009/05001/Comparison_Of_Body_Fat_Content_And_Distribution_Of.2807.aspxpor
dc.subjectFisioterapiapor
dc.subjectReabilitaçãopor
dc.subjectPolineuropatia amiloidótica familiarpor
dc.subjectGordura corporalpor
dc.titleComparison of body fat content and distribution of familial amyloidotic polyneuropathy patients versus healthy subjectspor
dc.typeconference object
dspace.entity.typePublication
oaire.citation.endPage402por
oaire.citation.startPage402por
oaire.citation.titleMedicine and Science in Sports Exercisepor
person.familyNameTomás
person.givenNameMaria Teresa
person.identifier438585
person.identifier.ciencia-id3010-19D6-C7A5
person.identifier.orcid0000-0003-0491-8903
person.identifier.ridN-1940-2013
person.identifier.scopus-author-id36700434200
rcaap.rightsrestrictedAccesspor
rcaap.typeconferenceObjectpor
relation.isAuthorOfPublication64ad74a4-4cd4-426e-a1ee-2ec846fdc6dd
relation.isAuthorOfPublication.latestForDiscovery64ad74a4-4cd4-426e-a1ee-2ec846fdc6dd

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Comparison of body fat content and distribution of familial amyloidotic.pdf
Size:
46.51 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

ESTeSL - Artigos