Processing and characterization of 3D dense chitosan pieces, for orthopedic applications, by adding plasticizers

Figueiredo, Lígia; Moura, Carla; Pinto, Luís F. V.; Ferreira, Frederico Castelo; Rodrigues, Alexandra

http://hdl.handle.net/10400.21/6091

Use this identifier to reference this record.

Name:	Description:	Size:	Format:
Processing and Characterization of 3D Dense Chitosan Pieces, for Orthopedic Applications, by Adding Plasticizers.pdf		4.03 MB	Adobe PDF	Download

Send Feedback

Authors

Figueiredo, Lígia

Moura, Carla

Pinto, Luís F. V.

Ferreira, Frederico Castelo

Rodrigues, Alexandra

Abstract(s)

In this work, plasticizer agents were incorporated in a chitosan based formulation, as a strategy to improve the fragile structure of chitosan based-materials. Three different plasticizers: ethylene glycol, glycerol and sorbitol, were blended with chitosan to prepare 3D dense chitosan specimens. The properties of the obtained structures were assessed for mechanical, microstructural, physical and biocompatibility behavior. The results obtained revealed that from the different specimens prepared, the blend of chitosan with glycerol has superior mechanical properties and good biological behavior, making this chitosan based formulation a good candidate to improve robust chitosan structures for the construction of bioabsorbable orthopedic implants.

Keywords

Chitosan Bioabsorbable implants Plasticizers Mechanical properties Citotocicity

URI

http://hdl.handle.net/10400.21/6091

Citation

FIGUEIREDO, Lígia; [et al] - Processing and characterization of 3D dense chitosan pieces, for orthopedic applications, by adding plasticizers. Procedia Engineering. ISSN 1877-7058. Vol. 110 (2015), pp. 175-182