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Processing and characterization of 3D dense chitosan pieces, for orthopedic applications, by adding plasticizers

2015-07-19Journal article Open access
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dc.contributor.authorFigueiredo, Lígia
dc.contributor.authorMoura, Carla
dc.contributor.authorPinto, Luís F. V.
dc.contributor.authorFerreira, Frederico Castelo
dc.contributor.authorRodrigues, Alexandra
dc.date.accessioned2016-04-26T16:01:59Z
dc.date.available2016-04-26T16:01:59Z
dc.date.issued2015-07-19
dc.description.abstractIn this work, plasticizer agents were incorporated in a chitosan based formulation, as a strategy to improve the fragile structure of chitosan based-materials. Three different plasticizers: ethylene glycol, glycerol and sorbitol, were blended with chitosan to prepare 3D dense chitosan specimens. The properties of the obtained structures were assessed for mechanical, microstructural, physical and biocompatibility behavior. The results obtained revealed that from the different specimens prepared, the blend of chitosan with glycerol has superior mechanical properties and good biological behavior, making this chitosan based formulation a good candidate to improve robust chitosan structures for the construction of bioabsorbable orthopedic implants.pt_PT
dc.identifier.citationFIGUEIREDO, Lígia; [et al] - Processing and characterization of 3D dense chitosan pieces, for orthopedic applications, by adding plasticizers. Procedia Engineering. ISSN 1877-7058. Vol. 110 (2015), pp. 175-182pt_PT
dc.identifier.doi10.1016/j.proeng.2015.06.182pt_PT
dc.identifier.issn1877-7058
dc.identifier.urihttp://hdl.handle.net/10400.21/6091
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevier Science BVpt_PT
dc.relation.publisherversionhttp://www.sciencedirect.com/science/article/pii/S1877705815011364pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectChitosanpt_PT
dc.subjectBioabsorbable implantspt_PT
dc.subjectPlasticizerspt_PT
dc.subjectMechanical propertiespt_PT
dc.subjectCitotocicitypt_PT
dc.titleProcessing and characterization of 3D dense chitosan pieces, for orthopedic applications, by adding plasticizerspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage182pt_PT
oaire.citation.startPage175pt_PT
oaire.citation.titleProcedia Engineeringpt_PT
oaire.citation.volume110pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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