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Setting up a collaborative European human biological monitoring study on occupational exposure to hexavalent chromium

2019-10Journal article Open access
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dc.contributor.authorSantonen, Tiina
dc.contributor.authorAlimonti, Alessandro
dc.contributor.authorBocca, Beatrice
dc.contributor.authorDuca, Radu Corneliu
dc.contributor.authorGalea, Karen S.
dc.contributor.authorGodderis, Lode
dc.contributor.authorGöen, Thomas
dc.contributor.authorGomes, Bruno
dc.contributor.authorHanser, Ogier
dc.contributor.authorIavicoli, Ivo
dc.contributor.authorJanasik, Beata
dc.contributor.authorJones, Kate
dc.contributor.authorKiilunen, Mirja
dc.contributor.authorKoch, Holger M.
dc.contributor.authorLeese, Elizabeth
dc.contributor.authorLeso, Veruscka
dc.contributor.authorLouro, Henriqueta
dc.contributor.authorNdaw, Sophie
dc.contributor.authorPorras, Simo P.
dc.contributor.authorRobert, Alain
dc.contributor.authorRuggieri, Flavia
dc.contributor.authorScheepers, Paul T. J.
dc.contributor.authorSilva, Maria J.
dc.contributor.authorViegas, Susana
dc.contributor.authorWasowicz, Wojciech
dc.contributor.authorCastano, Argelia
dc.contributor.authorSepai, Ovnair
dc.date.accessioned2019-07-17T11:51:17Z
dc.date.available2019-07-17T11:51:17Z
dc.date.issued2019-10
dc.descriptionHorizon 2020 - Grant agreement no. 733032pt_PT
dc.description.abstractThe EU human biomonitoring initiative, HBM4EU, aims to coordinate and advance human biomonitoring (HBM) across Europe. Within its remit, the project is gathering new, policy-relevant, EU-wide data on occupational exposure to relevant priority chemicals and developing new approaches for occupational biomonitoring. In this manuscript, the hexavalent chromium (Cr(VI)) study design is presented as the first example of this HBM4EU approach. This study involves eight European countries and plans to recruit 400 workers performing Cr(VI) surface treatment e.g. electroplating or stainless steel welding activities. The aim is to collect new data on current occupational exposure to Cr(VI) in Europe and to test new methods for Cr biomonitoring, specifically the analysis of Cr(VI) in exhaled breath condensate (EBC) and Cr in red blood cells (RBC) in addition to traditional urinary total Cr analyses. Furthermore, exposure data will be complemented with early biological effects data, including genetic and epigenetic effects. Personal air samples and wipe samples are collected in parallel to help to inform the biomonitoring results. We present standard operational procedures (SOPs) to support the harmonized methodologies for the collection of occupational hygiene and HBM samples in different countries.pt_PT
dc.description.versioninfo:eu-repo/semantics/acceptedVersionpt_PT
dc.identifier.citationSantonen T, Alimonti A, Bocca B, Duca RC, Galea KS, Viegas S, et al. Setting up a collaborative European human biological monitoring study on occupational exposure to hexavalent chromium. Environ Res. 2019;177:108583.pt_PT
dc.identifier.doi10.1016/j.envres.2019.108583pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.21/10306
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relationHorizon 2020 - Grant agreement no. 733032pt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S0013935119303809?via%3Dihubpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectHexavalent chromiumpt_PT
dc.subjectBiomonitoringpt_PT
dc.subjectOccupational exposurept_PT
dc.subjectExhaled breath condensatept_PT
dc.subjectWeldingpt_PT
dc.subjectElectroplatingpt_PT
dc.subjectEffect markerspt_PT
dc.subjectMulticenter studypt_PT
dc.titleSetting up a collaborative European human biological monitoring study on occupational exposure to hexavalent chromiumpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.startPage108583pt_PT
oaire.citation.startPage108583pt_PT
oaire.citation.titleEnvironmental Researchpt_PT
oaire.citation.volume177pt_PT
person.familyNameViegas
person.givenNameSusana
person.identifier248817
person.identifier.ciencia-idA919-7318-63DC
person.identifier.orcid0000-0003-1015-8760
person.identifier.ridI-4053-2012
person.identifier.scopus-author-id35270591500
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication13115332-43f7-4048-a8a5-2f2b855a8c92
relation.isAuthorOfPublication.latestForDiscovery13115332-43f7-4048-a8a5-2f2b855a8c92

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