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Evaluating deviations in prostatectomy patients treated with IMRT

2016-05Journal article Restricted access
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dc.contributor.authorSá, Ana Cravo
dc.contributor.authorPeres, Ana
dc.contributor.authorPereira, Mónica
dc.contributor.authorCoelho, Carina Marques
dc.contributor.authorMonsanto, Fátima
dc.contributor.authorMacedo, Ana
dc.contributor.authorLamas, Adrian
dc.date.accessioned2016-06-29T11:44:30Z
dc.date.available2016-06-29T11:44:30Z
dc.date.issued2016-05
dc.description.abstractAim - To evaluate the deviations in prostatectomy patients treated with IMRT in order to calculate appropriate margins to create the PTV. Background - Defining inappropriate margins can lead to underdosing in target volumes and also overdosing in healthy tissues, increasing morbidity. Material and methods - 223 CBCT images used for alignment with the CT planning scan based on bony anatomy were analyzed in 12 patients treated with IMRT following prostatectomy. Shifts of CBCT images were recorded in three directions to calculate the required margin to create PTV. Results and discussion - The mean and standard deviation (SD) values in millimetres were −0.05 ± 1.35 in the LR direction, −0.03 ± 0.65 in the SI direction and −0.02 ± 2.05 the AP direction. The systematic error measured in the LR, SI and AP direction were 1.35 mm, 0.65 mm, and 2.05 mm with a random error of 2.07 mm; 1.45 mm and 3.16 mm, resulting in a PTV margin of 4.82 mm; 2.64 mm, and 7.33 mm, respectively. Conclusion - With IGRT we suggest a margin of 5 mm, 3 mm and 8 mm in the LR, SI and AP direction, respectively, to PTV1 and PTV2. Therefore, this study supports an anisotropic margin expansion to the PTV being the largest expansion in the AP direction and lower in SI.pt_PT
dc.identifier.citationSá AC, Peres A, Pereira M, Coelho CM, Monsanto F, Macedo A, et al. Evaluating deviations in prostatectomy patients treated with IMRT. Rep Pract Oncol Radiother. 2016;21(3):266-70.pt_PT
dc.identifier.doi10.1016/j.rpor.2015.11.004pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.21/6255
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttp://www.sciencedirect.com/science/article/pii/S1507136715001595pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectRadiotherapypt_PT
dc.subjectProstate cancerpt_PT
dc.subjectIntensity modulated radiotherapypt_PT
dc.subjectPlanning target volume marginpt_PT
dc.subjectCone beam computed tomographypt_PT
dc.subjectGeometric uncertaintypt_PT
dc.titleEvaluating deviations in prostatectomy patients treated with IMRTpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage270pt_PT
oaire.citation.issue3pt_PT
oaire.citation.startPage266pt_PT
oaire.citation.titleReports of Practical Oncology & Radiotherapypt_PT
oaire.citation.volume21pt_PT
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT

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