Characterization of rotavirus infection in children with acute gastroenteritis in Bengo province, Northwestern Angola, prior to vaccine introduction

Gasparinho, Carolina; Piedade, João; Mirante, Maria Clara; Mendes, Cristina; Mayer, Carlos; Nery, Susana Vaz; Brito, Miguel; Istrate, Claudia

http://hdl.handle.net/10400.21/7029

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Abstract(s)

Rotavirus group A (RVA) is considered the leading cause of pediatric diarrhea, responsible for the high burden of diarrheal diseases in sub-Saharan Africa. Despite recent studies, the existent data are scarce for some African countries like Angola, a country with one of the highest RVA-related death estimates. The aim of this study was to determine the RVA detection rate and circulating genotypes in children less than five years of age with acute gastroenteritis attended at the Bengo General Hospital in Caxito, Bengo province, Angola, before vaccine introduction.

Keywords

Angola Antigens, viral Capsid proteins Children Child, preschool Diarrhea Feces Female Gastroenteritis Genotype Humans Infant Male Molecular typing Prevalence Rotavirus Rotavirus infections Vaccines Vomiting Phylogeny

URI

http://hdl.handle.net/10400.21/7029

Citation

Gasparinho C, Piedade J, Mirante MC, Mendes C, Mayer C, Brito M, et al. Characterization of rotavirus infection in children with acute gastroente ritis in Bengo province, Northwestern Angola, prior to vaccine introduction. PLoS ONE. 2017;12(4):e0176046.