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Gene expression regulation and lineage evolution: the North and South tale of the hybrid polyploid Squalius alburnoides complex

2010-11Journal article Open access
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dc.contributor.authorPala, Irene
dc.contributor.authorSchartl, Manfred
dc.contributor.authorBrito, Miguel
dc.contributor.authorMalta-Vacas, Joana
dc.contributor.authorCoelho, Maria Manuela
dc.date.accessioned2014-01-03T22:26:15Z
dc.date.available2014-01-03T22:26:15Z
dc.date.issued2010-11
dc.description.abstractThe evolution of hybrid polyploid vertebrates, their viability and their perpetuation over evolutionary time have always been questions of great interest. However, little is known about the impact of hybridization and polyploidization on the regulatory networks that guarantee the appropriate quantitative and qualitative gene expression programme. The Squalius alburnoides complex of hybrid fish is an attractive system to address these questions, as it includes a wide variety of diploid and polyploid forms, and intricate systems of genetic exchange. Through the study of genome-specific allele expression of seven housekeeping and tissue-specific genes, we found that a gene copy silencing mechanism of dosage compensation exists throughout the distribution range of the complex. Here we show that the allele-specific patterns of silencing vary within the complex, according to the geographical origin and the type of genome involved in the hybridization process. In southern populations, triploids of S. alburnoides show an overall tendency for silencing the allele from the minority genome, while northern population polyploids exhibit preferential biallelic gene expression patterns, irrespective of genomic composition. The present findings further suggest that gene copy silencing and variable expression of specific allele combinations may be important processes in vertebrate polyploid evolution.por
dc.identifier.citationPala I, Schartl M, Brito M, Malta Vacas J, Coelho MM. Gene expression regulation and lineage evolution: the North and South tale of the hybrid polyploid Squalius alburnoides complex. Proc Biol Sci. 2010;277(1699):3519-25.por
dc.identifier.issn1471-2954
dc.identifier.urihttp://hdl.handle.net/10400.21/3069
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherRoyal Society Publishingpor
dc.relation.publisherversionhttp://rspb.royalsocietypublishing.org/content/277/1699/3519.full.pdf+htmlpor
dc.subjectBiological evolutionpor
dc.subjectCyprinidaepor
dc.subjectDNA/geneticspor
dc.subjectGene expression profilingpor
dc.subjectGene expression regulationpor
dc.subjectPolyploidypor
dc.subjectRNA/geneticspor
dc.titleGene expression regulation and lineage evolution: the North and South tale of the hybrid polyploid Squalius alburnoides complexpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage3525por
oaire.citation.startPage3519por
oaire.citation.titleProceedings of the Royal Society. Biological sciencespor
oaire.citation.volume277por
person.familyNameBrito
person.givenNameMiguel
person.identifier.ciencia-id231F-F341-7E93
person.identifier.orcid0000-0001-6394-658X
person.identifier.ridA-7970-2016
person.identifier.scopus-author-id35224551000
rcaap.rightsopenAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublication4252d8e0-800c-4d67-8b13-0b711d860669
relation.isAuthorOfPublication.latestForDiscovery4252d8e0-800c-4d67-8b13-0b711d860669

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