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Manual segmentation of 12 layers of the retina and choroid through SD-OCT in intermediate AMD: repeatability and reproducibility

2021-07Journal article Open access
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dc.contributor.authorCamacho, Pedro
dc.contributor.authorDutra-Medeiros, Marco
dc.contributor.authorSalgueiro, Luís
dc.contributor.authorSadio, Sílvia
dc.contributor.authorRosa, Paulo C.
dc.date.accessioned2021-07-30T08:44:51Z
dc.date.available2021-07-30T08:44:51Z
dc.date.issued2021-07
dc.description.abstractPurpose: To evaluate the repeatability and reproducibility of the segmentation of 12 layers of the retina and the choroid, performed manually by SD-OCT, along the horizontal meridian at three different temporal moments, and to evaluate its concordance with the same measurements performed by two other operators in intermediate AMD. Methods: A cross-sectional study of 40 eyes from 40 subjects with intermediate AMD was conducted. The segmentation was performed manually, using SD-OCT. The 169 measurements per eye were repeated at three-time points to study the intra-operator variability. The same process was repeated a single time by two different trained operators for the inter-operator variability. Results: Forty participants (28 women and 12 men) were enrolled in this study, with an average age of 76.4 ± 8.2 (range, 55–92 years). Overall, the maximum values of the various structures were found in the 3 mm of the macula. Intra-operator variability: the highest ICC values turned out to be discovered in thicker locations. inter-operator variability: except correlation values of 0.826 (0.727; 0.898) obtained in the OPL (T2.5) and 0.634 (0.469; 0.771) obtained in the IPL (N2), all other correlation values were >0.92, in most cases approaching higher values like 0.98. Conclusion: The measurements of several layers of the retina and the choroid achieved at 13 locations presented good repeatability and reproducibility. Manual quantification is still an alternative for the weaknesses of automatic segmentation. Locations of greatest concordance should be those used for clinical control and monitoring.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCamacho P, Dutra-Medeiros M, Salgueiro L, Sadio S, Rosa PC. Manual segmentation of 12 layers of the retina and choroid through SD-OCT in intermediate AMD: repeatability and reproducibility. J Ophthalmic Vis Res. 2021;16(3):384-92.pt_PT
dc.identifier.doi10.18502/jovr.v16i3.9435pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.21/13586
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherKnowledge Ept_PT
dc.relation.publisherversionhttps://knepublishing.com/index.php/JOVR/article/view/9435pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/pt_PT
dc.subjectOphthalmologypt_PT
dc.subjectOrthopticspt_PT
dc.subjectData accuracypt_PT
dc.subjectDiagnostic imagingpt_PT
dc.subjectMacular degenerationpt_PT
dc.titleManual segmentation of 12 layers of the retina and choroid through SD-OCT in intermediate AMD: repeatability and reproducibilitypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage392pt_PT
oaire.citation.issue3pt_PT
oaire.citation.startPage384pt_PT
oaire.citation.titleJournal of Ophthalmic and Vision Researchpt_PT
oaire.citation.volume16pt_PT
person.familyNameCamacho
person.givenNamePedro
person.identifier.ciencia-id271F-B4E1-014E
person.identifier.orcid0000-0002-2986-5652
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationc41e9c52-157e-4375-8005-b609cfc374e7
relation.isAuthorOfPublication.latestForDiscoveryc41e9c52-157e-4375-8005-b609cfc374e7

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