Occupational exposure to endotoxins: forklift drivers

Costa-Pereira, Cristiana; Lage, Bruna; Viegas, Carla; Teixeira, João Paulo

Publication

Occupational exposure to endotoxins: forklift drivers

2019-06Conference object

dc.contributor.author	Costa-Pereira, Cristiana
dc.contributor.author	Lage, Bruna
dc.contributor.author	Viegas, Carla
dc.contributor.author	Teixeira, João Paulo
dc.date.accessioned	2019-07-25T16:17:01Z
dc.date.available	2019-07-25T16:17:01Z
dc.date.issued	2019-06
dc.description	Project EXPOsE, nº 23222 (02/SAICT/2016)	pt_PT
dc.description.abstract	Many studies have already associated endotoxin exposure, especially in workplaces, to airways disease, yet threshold limit values have not been set, nor a standardized procedure for the analysis of endotoxin levels. Inhaled endotoxins may cause bronchial asthma and may increase the allergic response in hypersensitive people. Endotoxins are biologically active lipopolysaccharides (LPSs) produced by the most external layer of cell walls of gram (−) bacteria. They are commonly found at workplaces where large amounts of bioaerosols are generated, like in waste sorting plants, where microorganisms growing on organic residue are present at high concentration in the air. Endotoxins are relatively heating stable so they are released into the air during cell growth and after cells’ death when the integrity of the cell wall is ruptured. Up to the present, endotoxin values are measured with non-uniform methods and therefore values are of limited benefit for assessment and limits’ establishment. In this study, eleven filters belonging to the filtration system from forklifts operating in one waste sorting industry located in the Lisbon region and one control filter were analyzed. The 11 filters were used in forklifts between 794 and 22,240 working h. All the assessed filters were composed by activated charcoal and belong to category 2 (pores typically from 3.0 μm or greater dimension) according to protection requirements (EN 15695) ensuring protection against dust inside the cabinet. In these settings, criteria for filter replacement in the air conditioning system are dependent on visual observation by the maintenance service to accomplish preventive maintenance program. Endotoxins levels were analyzed following the European Standard (2003) EN 14031 and varied between 3,6 EU/cm2 and > 625 EU/cm2. Considering that standard filters have an area of about 1226 cm2, the total charge of endotoxins in the studied filters ranges from 4382 EU to 766 250 EU which raises questions about the security and for how long is safe to keep the filters in use in this and other particular indoor settings.	pt_PT
dc.description.version	info:eu-repo/semantics/publishedVersion	pt_PT
dc.identifier.citation	Costa-Pereira C, Lage B, Viegas C, Teixeira JP. Occupational exposure to endotoxins: forklift drivers. In: XIV Congresso da Associação Brasileira de Mutagênese e Genômica Ambiental, Dall’Onder Grande Hotel, Bento Gonçalves – RS (Brasil), 3-6 de junho de 2019. poster 40.	pt_PT
dc.identifier.uri	http://hdl.handle.net/10400.21/10375
dc.language.iso	eng	pt_PT
dc.peerreviewed	yes	pt_PT
dc.relation	Project nº 23222 (02/SAICT/2016)	pt_PT
dc.relation	Project EXPOsE	pt_PT
dc.relation.publisherversion	https://congressomutagen.org/index.php?menu=programacao	pt_PT
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/	pt_PT
dc.subject	Occupational health	pt_PT
dc.subject	Occupational exposure	pt_PT
dc.subject	Endotoxins	pt_PT
dc.subject	Respiratory disease	pt_PT
dc.subject	Portugal	pt_PT
dc.subject	Project nº 23222 (02/SAICT/2016)	pt_PT
dc.subject	Project EXPOsE	pt_PT
dc.title	Occupational exposure to endotoxins: forklift drivers	pt_PT
dc.type	conference object
dspace.entity.type	Publication
person.familyName	Viegas
person.givenName	Carla
person.identifier.ciencia-id	EE1E-C639-D70F
person.identifier.orcid	0000-0002-1545-6479
person.identifier.rid	B-7217-2013
person.identifier.scopus-author-id	55443609700
rcaap.rights	openAccess	pt_PT
rcaap.type	conferenceObject	pt_PT
relation.isAuthorOfPublication	b5fa5da4-50c3-4b88-ae20-1bc63cb485f7
relation.isAuthorOfPublication.latestForDiscovery	b5fa5da4-50c3-4b88-ae20-1bc63cb485f7