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Preliminary results of an animal model validation of chronic experimental colitis

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Inflammatory bowel disease (IBD): chronic inflammatory disease of the gastrointestinal (GI) tract characterized by recurrent ulceration. IBD prevalence exceeding 0,5% of the population in westernized countries. IBD manifests into several intestinal and extra-intestinal symptoms, mainly related to inflammation. IBD includes Crohn’s disease and Ulcerative colitis. Aim of the study: evaluate the efficacy of new drugs in IBD through an animal model of TNBS-induced chronic colitis.

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Inflammatory bowel disease Chronic colitis Crohn disease Ulcerative colitis Animal model

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Silva IJ, Pinto R, Mateus V. Preliminary results of an animal model validation of chronic experimental colitis. In: II BootCamp H&TRC 2020, Convento de Nossa Senhora da Arrábida, 16 de janeiro de 2020.

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