Unusual cause for smoldering dysphagia

Figueiredo, Pedro C; Pinto-Marques, Pedro; Borralho-Nunes, Paula; Freitas, João

Publication

Unusual cause for smoldering dysphagia

2014-04Journal article

dc.contributor.author	Figueiredo, Pedro C
dc.contributor.author	Pinto-Marques, Pedro
dc.contributor.author	Borralho-Nunes, Paula
dc.contributor.author	Freitas, João
dc.date.accessioned	2016-02-23T17:38:11Z
dc.date.available	2016-02-23T17:38:11Z
dc.date.issued	2014-04
dc.description.abstract	A 30-year-old black woman presented with heartburn and odynophagia. She had a 2-year history of Behçet’s disease and systemic lupus erythematosus and had been treated with colchicine, hydroxychloroquine, and sucralfate. Odynophagia was not related to the presence of oral ulcers as they were painless and when they were in remission the patient would still intermittently complain of substernal pain. The patient underwent upper digestive endoscopy that revealed only small mucosal irregularities in the upper third of the esophagus. Biopsies of these segments showed marked acanthosis and papillomatosis of the squamous epithelium as well as intense lymphoplasmacytic infiltrate with an increased number of intraepithelial lymphocytes (IEL). There were neither granulocytes nor signs of viral infection. The endoscopic findings were then attributed to regenerative changes of the epithelium and the patient was started on a proton pump inhibitor (PPI), assuming gastroesophageal reflux disease (GERD). During the following years there were flare-ups of rheumatologic disease activity due to the patient’s lack of adherence to therapy. However, there was no correlation of the patient’s maintained (although scarce) complaints of transitory dysphagia and substernal pain.	pt_PT
dc.identifier.citation	Figueiredo PC, Pinto-Marques P, Borralho-Nunes P, Freitas J. Unusual cause for smoldering dysphagia. Dysphagia. 2014;29(2):283-5.	pt_PT
dc.identifier.doi	10.1007/s00455-013-9489-2	pt_PT
dc.identifier.uri	http://hdl.handle.net/10400.21/5723
dc.language.iso	eng	pt_PT
dc.peerreviewed	yes	pt_PT
dc.publisher	Springer	pt_PT
dc.relation.publisherversion	http://link.springer.com/article/10.1007%2Fs00455-013-9489-2	pt_PT
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/	pt_PT
dc.subject	Dysphagia	pt_PT
dc.subject	Deglutition	pt_PT
dc.subject	Endoscopy	pt_PT
dc.subject	Esophagitis	pt_PT
dc.subject	Lymphocytosis	pt_PT
dc.title	Unusual cause for smoldering dysphagia	pt_PT
dc.type	journal article
dspace.entity.type	Publication
oaire.citation.endPage	285	pt_PT
oaire.citation.startPage	283	pt_PT
oaire.citation.title	Dysphagia	pt_PT
oaire.citation.volume	29	pt_PT
rcaap.rights	openAccess	pt_PT
rcaap.type	article	pt_PT