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Trends in COVID-19 patient characteristics and mortality throughout the pandemic: insights from a portuguese single-centre study

2024-12Conference paper Open access
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authorProfile.emailbiblioteca@isel.pt
datacite.subject.fosEngenharia e Tecnologia::Engenharia Química
dc.contributor.authorVon Rekowski, Cristiana
dc.contributor.authorPinto, Iola
dc.contributor.authorHenrique Fonseca, Tiago Alexandre
dc.contributor.authorAraújo, Rúben Alexandre Dinis
dc.contributor.authorFerreira, Artur
dc.contributor.authorCalado, Cecília
dc.contributor.authorBento, Luís
dc.contributor.editorDomingues, Nuno
dc.contributor.editorTomar, Rajesh Singh
dc.contributor.editorMahamud, Tosaporn
dc.date.accessioned2025-04-07T08:58:31Z
dc.date.available2025-04-07T08:58:31Z
dc.date.issued2024-12
dc.description.abstractAs SARS-CoV-2 continues to circulate globally and new variants emerge, it remains relevant to gather data on the affected patients’ clinical characteristics and outcomes to understand how individual factors and public health measures affect prognosis. Thus, we analyzed data of 870 ICU patients admitted for COVID-19 across two distinct phases of the pandemic: before and after the introduction of immunization. Experimental results showed that vaccination significantly impacted patient demographics after the third wave, and that waves number two and three, dominated by the EU1 and Alpha variants, had higher mortality. Older age, the need for invasive mechanical ventilation, and hematologic cancer were significantly associated with an increased risk of death in the adjusted multivariable model (AUC: 0.778, 95% CI 0.746-0.810, p<0.001). As the pandemic progressed, while some public health interventions influenced the observed trends, individual patient characteristics had a more substantial impact on their outcome.eng
dc.identifier.citationVon Rekowski, C. P. et al. Trends in COVID-19 patient characteristics and mortality throughout the pandemic: insights from a portuguese single-centre study. In 4th ROME International Conference on Challenges in Engineering, Medical, Economics and Education: Research & Solutions, Rome, Italy, 2024, pp. 32-38, doi: https://doi.org/10.17758/EARES19
dc.identifier.doi10.17758/EARES19
dc.identifier.isbn978-989-9121-43-0
dc.identifier.urihttp://hdl.handle.net/10400.21/21762
dc.language.isoeng
dc.peerreviewedyes
dc.publisherEARET
dc.relation.hasversionhttps://earet.org/proceedingspdf.php?id=415
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectCOVID-19 waves
dc.subjectCOVID-19 vaccination
dc.subjectIntensive care unit
dc.subjectMortality
dc.titleTrends in COVID-19 patient characteristics and mortality throughout the pandemic: insights from a portuguese single-centre studyeng
dc.typeconference paper
dspace.entity.typePublication
oaire.citation.conferenceDate2024-12-04
oaire.citation.conferencePlaceRome, Italy
oaire.citation.endPage38
oaire.citation.startPage32
oaire.citation.title4th ROME International Conference on Challenges in Engineering, Medical, Economics and Education: Research & Solutions
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameVon Rekowski
person.familyNamePinto
person.familyNameHenrique Fonseca
person.familyNameAraújo
person.familyNameFerreira
person.familyNameCalado
person.givenNameCristiana
person.givenNameIola
person.givenNameTiago Alexandre
person.givenNameRúben Alexandre Dinis
person.givenNameArtur
person.givenNameCecília
person.identifierR-000-ME5
person.identifier1960990
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person.identifier.ciencia-id9A18-BFDC-ED95
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person.identifier.ciencia-id9418-E320-3177
person.identifier.orcid0009-0009-6843-1935
person.identifier.orcid0000-0002-2945-1441
person.identifier.orcid0000-0003-0741-2211
person.identifier.orcid0000-0002-9369-6486
person.identifier.orcid0000-0002-6508-0932
person.identifier.orcid0000-0002-5264-9755
person.identifier.ridAAL-4377-2020
person.identifier.ridE-2102-2014
person.identifier.scopus-author-id34969436900
person.identifier.scopus-author-id35315359300
person.identifier.scopus-author-id6603163260
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