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Cardiac PET/CT with Rb-82: optimization of image acquisition and reconstruction parameters

2017-02Journal article Open access
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dc.contributor.authorChilra, P.
dc.contributor.authorGnesin, S.
dc.contributor.authorAllenbach, G.
dc.contributor.authorMonteiro, M.
dc.contributor.authorPrior, J. O.
dc.contributor.authorVieira, Lina
dc.contributor.authorPires Jorge, J. A.
dc.date.accessioned2017-06-08T14:08:47Z
dc.date.available2017-06-08T14:08:47Z
dc.date.issued2017-02
dc.description.abstractOur aim was to characterize the influence of time-of-flight (TOF) and point spread function (PSF) recovery corrections, as well as ordered subset expectation maximization (OSEM) reconstruction parameters, in (82)Rb PET/CT quantification of myocardial blood flow (MBF) and myocardial flow reserve (MFR). Rest and stress list-mode dynamic (82)Rb PET acquisition data from 10 patients without myocardial flow defects and 10 patients with myocardial blood flow defects were reconstructed retrospectively. OSEM reconstructions were performed with Gaussian filters of 4, 6, and 8 mm, different iterations, and subset numbers (2 × 24; 2 × 16; 3 × 16; 4 × 16). Rest and stress global, regional, and segmental MBF and MFR were computed from time activity curves with FlowQuant(©) software. Left ventricular segmentation using the 17-segment American Heart Association model was obtained.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationChilra P, Gnesin S, Allenbach G, Monteiro M, Prior JO, Vieira L, et al. Cardiac PET/CT with Rb-82: optimization of image acquisition and reconstruction parameters. EJNMMI Phys. 2017;4(1):10pt_PT
dc.identifier.doi10.1186/s40658-017-0178-3pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.21/7176
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringerOpenpt_PT
dc.relation.publisherversionhttps://ejnmmiphys.springeropen.com/articles/10.1186/s40658-017-0178-3pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nd/4.0/pt_PT
dc.subjectRb-82pt_PT
dc.subjectMyocardial blood flowpt_PT
dc.subjectMyocardial flow reservept_PT
dc.subjectCardiac PET/CT reconstructionpt_PT
dc.titleCardiac PET/CT with Rb-82: optimization of image acquisition and reconstruction parameterspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.startPage10pt_PT
oaire.citation.titleEJNMMI Physicspt_PT
oaire.citation.volume4pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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