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Non-miotic improvement in binocular near vision with a topical compound formula for presbyopia correction

2023-01Journal article Open access
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dc.contributor.authorVejarano, Felipe
dc.contributor.authorAlió, Jorge
dc.contributor.authorIribarren, Rafael
dc.contributor.authorLança, Carla
dc.date.accessioned2023-02-14T13:06:58Z
dc.date.available2023-02-14T13:06:58Z
dc.date.issued2023-01
dc.description.abstractIntroduction: The aim of this case series was to examine the association between unaided binocular visual acuity for near vision and pupil change after the instillation of a special topical formulation for presbyopia treatment. Methods: This was a case series consisting of consecutive participants with presbyopia aged 40-70 years who were tested for visual acuity and pupil diameter before and 2 h after the instillation of a formulation of pilocarpine and phenylephrine drops (FOV Tears) for presbyopia. Participants underwent subjective refraction, photopic and scotopic pupil diameter measurement, and unaided monocular and binocular visual acuity testing by logMAR for distance and near vision both pre- and post-instillation of eye drops. Results: The study enrolled 363 subjects (n = 176 women, 48%) with a mean (± standard deviation) age of 50.4 ± 5.8 years. The mean spherical equivalent (SE) changed significantly (- 0.17 Diopters) after the instillation of the FOV Tears formulation (p < 0.001). Post-instillation of eye drops, the scotopic pupil diameter decreased by 0.97 ± 0.98 mm, and the near visual acuity by logMAR improved significantly by nearly two lines (p < 0.01). In the linear regression analyses, age (p < 0.001) and SE pre-drop instillation (p < 0.001) were associated with unaided binocular visual acuity. The changes in photopic pupil diameter and scotopic pupil diameter were not associated with unaided binocular visual acuity. Conclusions: The use of the pilocarpine and phenylephrine formulation (FOV Tears) improved binocular visual acuity for near vision in presbyopic patients, and the effect was independent of pupil change.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationVejarano F, Alió J, Iribarren R, Lança C. Non-miotic improvement in binocular near vision with a topical compound formula for presbyopia correction. Ophthalmol Ther. 2023;12:1023-24.pt_PT
dc.identifier.doi10.1007/s40123-023-00648-6pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.21/15573
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringerpt_PT
dc.relation.publisherversionhttps://link.springer.com/article/10.1007/s40123-023-00648-6pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectOphthalmologypt_PT
dc.subjectNear visual acuitypt_PT
dc.subjectPhenylephrinept_PT
dc.subjectPilocarpinept_PT
dc.subjectPresbyopiapt_PT
dc.subjectPupil diameterpt_PT
dc.titleNon-miotic improvement in binocular near vision with a topical compound formula for presbyopia correctionpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage1024pt_PT
oaire.citation.startPage1013pt_PT
oaire.citation.titleOphthalmology and Therapypt_PT
oaire.citation.volume12pt_PT
person.familyNameLança
person.givenNameCarla
person.identifier.ciencia-id601A-6412-BF2F
person.identifier.orcid0000-0001-9918-787X
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication0320b455-ee19-4670-8bf2-10dce9de1bec
relation.isAuthorOfPublication.latestForDiscovery0320b455-ee19-4670-8bf2-10dce9de1bec

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