Poly(D,L-lactic acid) scaffolds as an innovative approach to the treatment of mixed S. aureus-C. albicans biofilms

Zegre, Miguel; Barros, J.; Ribeiro, I. A.; Santos, C.; Aranha Caetano, Liliana; Gonçalves, L.; Monteiro, F.; Ferraz, M.; Bettencourt, A.

http://hdl.handle.net/10400.21/16735

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Authors

Aranha Caetano, Liliana

Abstract(s)

Problem - Bone infections associated with polymicrobial biofilm formation; mixed bacterial-fungal biofilm infection; Staphylococcus aureus and Candida albicans most described microbials. Strategy - Local drug delivery scaffolds; development of poly-DL-lactic acid (PDLLA) scaffolds; co-delivery of antibacterial and antifungal drugs; minocycline and voriconazole as model drugs.

Keywords

Bone infection Minocycline Voriconazole

URI

http://hdl.handle.net/10400.21/16735

Citation

Zegre M, Barros J, Ribeiro IA, Santos C, Caetano LA, Gonçalves L, et al. Poly(D,L-lactic acid) scaffolds as an innovative approach to the treatment of mixed S. aureus-C. albicans biofilms. In: X Congresso Iberoamericano de Ciências Farmacêuticas, Universidade de Coimbra, 26-28 de outubro de 2023.