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Assessment of azole resistance in healthcare facilities

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Azole resistance among fungal species has been increasing worldwide in recent years, representing a public health concern in the management of fungal infections. The complex environment of healthcare facilities, where microbial agents, including fungal contamination, are present must be controlled in order to protect susceptible patients. In this study, a scoping review was performed regarding the assessments of fungal resistance to azole drugs performed from 2000 to 2019 on healthcare facilities’ indoor environments. Both active and passive sampling was used in the 12 studies found. Aspergillus section Fumigati was the fungal species more frequently described, and itraconazole-resistance the most common type of azole resistance. EUCAST methods were used in four studies. This article highlights the need for surveillance of azole-resistance in healthcare facilities to ensure the quality of their environment and reduce the spread of fungal resistance.

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Active sampling Azole resistance Fungal analysis Hospital Passive sampling

Contexto Educativo

Citação

Caetano LA, Costa N, Oliveira C. Assessment of azole resistance in healthcare facilities. In: Zaragoza O, Casadevall A, editors. Encyclopedia of mycology (Vol. 2). Amsterdam: Elsevier; 2021. p. 159-67.

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