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Advisor(s)
Abstract(s)
Human biomonitoring consists, in one hand by the research and investigation of environmental hazards and, in other hand in risk estimating of developing cancer by exposure to those conditions. Since carcinogenesis is a process that takes time, the biomarkers applied to recognize abnormal biological events have been developed in molecular epidemiological studies. The biomarkers allow the quantification and identification of the progression of normal to abnormal biological conditions at a molecular level. In general, biomarkers can be classified in exposure, effect and genetic susceptibility. Genotoxicity biomarkers are a sub-type of effect biomarkers and are widely used in the assessment of genomic effects caused by exposure – environmental or occupational, being considered predictors of carcinogenesis development. Taken together, and inserted in a biomonitoring program, probably is the most growing tool available nowadays for the prevention of health effects from occupational exposure to chemicals. Ethical considerations should always be taken into consideration in the planning and implementation of the biomarkers involved.
Description
Keywords
Occupational exposure Biological monitoring Biomarkers Public health
Citation
Ladeira C, Viegas S. Application of human biomonitoring programmes in occupational exposure contexts: an overview. In: Arezes et al, editors. Proceedings book of the International Symposium on Occupational Safety and Hygiene – SHO2016. Guimarães: SPOSHO; 2016. p. 123-5.