Repository logo
 
Publication

Cytostatics occupational exposure: genotoxic effects assessment

2014-09Conference object Open access
Simple item page
dc.contributor.authorLadeira, Carina
dc.contributor.authorViegas, Susana
dc.contributor.authorCarolino, Elisabete
dc.contributor.authorGomes, M. C.
dc.contributor.authorBrito, Miguel
dc.date.accessioned2014-10-14T11:10:44Z
dc.date.available2014-10-14T11:10:44Z
dc.date.issued2014-09
dc.description.abstractThe use of cytostatics drugs in anticancer therapy is increasing. Health care workers can be occupationally exposed to these drugs classified as carcinogenic, mutagenic or teratogenic. Workers may be exposed to this drug, being in the hospital settings the main focus dwelled upon the pharmacy, and nursing personnel. Although the potential therapeutic benefits of hazardous drugs outweigh the risks of side effects for ill patients, exposed health care workers can have the same side effects with no therapeutic benefit. The exposure to these substances is epidemiologically linked to cancer and nuclear changes detected by the cytokinesis-block micronucleus test (CBMN). This method is extensively used in molecular epidemiology, since it determines several biomarkers of genotoxicity, such as micronuclei (MN), which are biomarkers of chromosomes breakage or loss, nucleoplasmic bridges (NPB), common biomarkers of chromosome rearrangement, poor repair and/or telomeres fusion, and nuclear buds (NBUD), biomarkers of elimination of amplified DNA.por
dc.description.sponsorshipAutoridade para as Condições de Trabalhopor
dc.identifier.citationLadeira C, Viegas S, Carolino E, Gomes MC, Brito M. Cytostatics occupational exposure: genotoxic effects assessment. In 3rd International Congress in Environmental Health – ICEH 2014, Porto (Portugal), 24-26 September 2014.por
dc.identifier.urihttp://hdl.handle.net/10400.21/3865
dc.language.isoengpor
dc.peerreviewedyespor
dc.relationProjeto 036APJ/09por
dc.relation.publisherversionhttp://www.iceh2014.pt.to/por
dc.subjectCytostatic drugspor
dc.subjectBiomonitoringpor
dc.subjectOccupational exposurepor
dc.subjectGenotoxicitypor
dc.subjectCytokinesis-blocked micronucleus assaypor
dc.titleCytostatics occupational exposure: genotoxic effects assessmentpor
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlacePortopor
person.familyNameLadeira
person.familyNameViegas
person.familyNameCarolino
person.familyNameBrito
person.givenNameCarina
person.givenNameSusana
person.givenNameElisabete
person.givenNameMiguel
person.identifier144237
person.identifier248817
person.identifier.ciencia-id801C-1BBA-1D9E
person.identifier.ciencia-idA919-7318-63DC
person.identifier.ciencia-id1216-EFA3-1E0F
person.identifier.ciencia-id231F-F341-7E93
person.identifier.orcid0000-0001-5588-0074
person.identifier.orcid0000-0003-1015-8760
person.identifier.orcid0000-0003-4165-7052
person.identifier.orcid0000-0001-6394-658X
person.identifier.ridJ-2572-2012
person.identifier.ridI-4053-2012
person.identifier.ridF-1012-2015
person.identifier.ridA-7970-2016
person.identifier.scopus-author-id36463788000
person.identifier.scopus-author-id35270591500
person.identifier.scopus-author-id25821697000
person.identifier.scopus-author-id35224551000
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
relation.isAuthorOfPublication1aef4b60-4197-436b-84ab-80d31cbaed33
relation.isAuthorOfPublication13115332-43f7-4048-a8a5-2f2b855a8c92
relation.isAuthorOfPublication77930d39-ed34-44dc-a4a6-9bf833e5e688
relation.isAuthorOfPublication4252d8e0-800c-4d67-8b13-0b711d860669
relation.isAuthorOfPublication.latestForDiscovery4252d8e0-800c-4d67-8b13-0b711d860669

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Cytostatics occupational exposure_genotoxic effects assessment.pdf
Size:
4.24 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

ESTeSL - Posters