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Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals

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Background - The use of antineoplastic drugs in cancer therapy is increasing due to their action in cancer cells. Carcinogenic, mutagenic and teratogenic effects. Some studies demonstrated that nurses and pharmacy personnel involved in preparation or administration are exposed to antineoplastic drugs. Aim: assess 5-Fluorouracil (5-FU) contamination on the surfaces of two Portuguese Hospitals (preparation and administration units). 5-FU is one of the most frequently antineoplastic agent used in Portuguese Hospitals and can be easily absorbed through the skin. This drug can be used as an marker of surfaces contamination and exposure and have been extensively discussed in other studies.

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Environmental health Fungal contamination Hospital Surfaces contamination Antineoplastic drugs Portugal

Citation

Viegas S, Pádua M, Gomes M. Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals. In International Symposium on Occupational Safety and Hygiene, Guimarães (Portugal), 13th to 14th February 2014.

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