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Authors
Advisor(s)
Abstract(s)
O cancro da próstata é o segundo tumor em incidência e mortalidade de entre as neoplasias malignas masculinas. Para uma adequada programação terapêutica é fundamental a caracterização e distinção entre os tumores confinados à próstata e os que assumem extensão prostática. A Ressonância Magnética é um exame de primeira linha no estudo da patologia prostática. Os clínicos prescritores têm demostrado dificuldades de acesso a este tipo de exames devido a diferentes condicionantes, nomeadamente listas de espera elevadas, as condições financeiras dos utentes, protocolos demorados e dispendiosos condicionando assim, o diagnóstico e naturalmente a terapêutica em tempo útil. Este estudo tem como objetivo principal, analisar, a partir da literatura, os protocolos de Ressonância Magnética da próstata abreviada aplicados ao carcinoma da próstata. O estudo é de carácter descritivo, secundário, de recuperação e análise critica da literatura. A estratégia de pesquisa foi desenvolvida no sentido de encontrar os potenciais artigos relevantes num conjunto de fontes, como: as bases de dados bibliográficas de biomedicina; bases de registos de ensaios clínicos randomizados e quase randomizados; repositórios científicos e sites agregados de bases bibliográficas. Após uma pesquisa em diferentes bases de dados e aplicados os critérios de inclusão, 17 estudos, orientados pela metodologia PRISMA foram selecionados para esta revisão sistemática. O estudo foi registado na PROSPERO e a ferramenta QUADAS-2 foi utilizada para avaliar a qualidade dos estudos incluídos. Reduzir os protocolos de Ressonância Magnética Multiparamétrica da próstata pode resolver vários desafios práticos atuais, como o desconforto e condições físicas dos pacientes. No entanto se o protocolo de Ressonância Magnética Biparamétrica fosse padronizado, aumentaria o número de exames realizados numa única sessão e abrangeria um maior número de pacientes.
ABSTRACT - Prostate cancer is the second tumor in incidence and mortality among male malignancies. For adequate therapeutic planning, it is essential to characterize and distinguish between tumors confined to the prostate and those that assume prostatic extension. Magnetic resonance imaging is a first-line exam in the study of prostatic pathology. Prescribing clinicians have shown difficulties in accessing this type of exam due to different constraints, namely long waiting lists, the financial conditions of users, and time-consuming and expensive protocols, thus conditioning the diagnosis and naturally the therapy in good time. The main objective of this study is to analyze, from the literature, the protocols of abbreviated Prostate Magnetic Resonance applied to prostate carcinoma. The study is of a descriptive, secondary nature, recovery, and critical analysis of the literature. The search strategy was developed to find potentially relevant articles in a set of sources, such as: biomedicine bibliographic databases; databases of randomized and quasi-randomized clinical trials; scientific repositories, and aggregate sites of bibliographic bases. After searching different databases and applying the inclusion criteria, 17 studies guided by the PRISMA methodology were selected for this systematic review. The study was registered in PROSPERO and the QUADAS-2 tool was used to assess the quality of the included studies. Reducing Prostate Multiparameter Magnetic Resonance protocols can solve several current practical challenges, such as discomfort and physical conditions of patients. However, if the Biparametric MRI protocol were standardized, the number of exams performed in a single session would increase and it would cover a larger number of patients.
ABSTRACT - Prostate cancer is the second tumor in incidence and mortality among male malignancies. For adequate therapeutic planning, it is essential to characterize and distinguish between tumors confined to the prostate and those that assume prostatic extension. Magnetic resonance imaging is a first-line exam in the study of prostatic pathology. Prescribing clinicians have shown difficulties in accessing this type of exam due to different constraints, namely long waiting lists, the financial conditions of users, and time-consuming and expensive protocols, thus conditioning the diagnosis and naturally the therapy in good time. The main objective of this study is to analyze, from the literature, the protocols of abbreviated Prostate Magnetic Resonance applied to prostate carcinoma. The study is of a descriptive, secondary nature, recovery, and critical analysis of the literature. The search strategy was developed to find potentially relevant articles in a set of sources, such as: biomedicine bibliographic databases; databases of randomized and quasi-randomized clinical trials; scientific repositories, and aggregate sites of bibliographic bases. After searching different databases and applying the inclusion criteria, 17 studies guided by the PRISMA methodology were selected for this systematic review. The study was registered in PROSPERO and the QUADAS-2 tool was used to assess the quality of the included studies. Reducing Prostate Multiparameter Magnetic Resonance protocols can solve several current practical challenges, such as discomfort and physical conditions of patients. However, if the Biparametric MRI protocol were standardized, the number of exams performed in a single session would increase and it would cover a larger number of patients.
Description
Mestrado em Radiações Aplicados às Tecnologias da Saúde
Keywords
Ressonância magnética Ressonância magnética biparamétrica Ressonância magnética multiparamétrica Protocolos Magnetic resonance Biparametric magnetic resonance Multiparametric magnetic resonance Protocols
Citation
Abreu VA. Otimização de protocolos abreviados em estudos de ressonância magnética no carcinoma da próstata: revisão sistemática [dissertation]. Lisboa: Escola Superior de Tecnologia da Saúde de Lisboa/Instituto Politécnico de Lisboa; 2023.
Publisher
Instituto Politécnico de Lisboa, Escola Superior de Tecnologia da Saúde de Lisboa