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Gold nanoflowers for colorimetric detection of NGAL antibodies

2026Comunicação em conferência Acesso restrito
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datacite.subject.fosEngenharia e Tecnologia::Engenharia Química
dc.contributor.authorSerafinelli, Caterina
dc.contributor.authorFantoni, Alessandro
dc.contributor.authorAlegria, Elisabete C. B. A.
dc.contributor.authorPacheco, Rita
dc.contributor.authorVieira, Manuela
dc.contributor.authorVieira, Manuela
dc.contributor.authorPacheco, Rita
dc.contributor.authorAlegria, Elisabete
dc.contributor.authorFantoni, Alessandro
dc.date.accessioned2026-09-22T14:08:25Z
dc.date.available2026-09-22T14:08:25Z
dc.date.issued2026
dc.description.abstractColorimetric sensors are a type of sensing platform enabling visual measurements that offers an instant report. Due to their intrinsic advantages, such as low cost, simplicity, low acquisition time and no need for expensive instrumentation, colorimetric transducers are attracting a growing attention for the PoC devices. In light of their brilliant colors arising from their Localized Surface Plasmon Resonance (LSPR), gold nanoparticles have revealed a great potential to develop new analytical techniques and advanced assays. Stimulated by the need of PoC devices for an affordable and real-time detection of biomarkers outside clinical environment, in this work we explore the potential of gold nanoflowers (AuNFs) as sensing system to integrate in a PoC device. Firstly, gold AuNFs functionalized with NGAL antibodies along with antibodies conjugated onto AuNFs surface binding their complementary antigens will be synthesized and their transmittance spectra measured. In a successive step, the measured spectra have been converted into vectors in the L*a*b*, xyY and RGB Color spaces by means of simulation study. Transferring the study into real world application, the AuNFs will be integrated into the fiber network of paper to create the plasmonic paper that will be the transducer of a colorimetric device.eng
dc.identifier.citationViega, S., Alegria, E. C. B. A., Pacheco, R., Fantoni, A., & Vieira, M. (2025). Gold nanoflowers for colorimetric detection of NGAL antibodies. In Colloidal Nanoparticles for Biomedical Applications XX (Proceedings of SPIE, Vol. 13336, Art. 133360C). SPIE. https://doi.org/10.1117/12.3100376
dc.identifier.doi10.1117/12.3100376
dc.identifier.issn0277-786X
dc.identifier.urihttp://hdl.handle.net/10400.21/23175
dc.language.isoeng
dc.peerreviewedyes
dc.publisherSPIE
dc.relationCentre of Technology and Systems
dc.relationSFRH/BD/09347/2021
dc.relationUIDB/00066/2020
dc.relationUIDP/00066/2020
dc.relationIPL/IDI&CA2023/LUMINA
dc.relation.hasversionhttps://www.webofscience.com/wos/woscc/full-record/WOS:001832568000015
dc.rights.uriN/A
dc.subjectAuNFsNGAL
dc.subjectAntibodiesColorimetric
dc.subjectdetectionCyber
dc.subjectPhysical System
dc.titleGold nanoflowers for colorimetric detection of NGAL antibodieseng
dc.typeconference paper
dspace.entity.typePublication
oaire.awardNumberUIDP/00066/2020
oaire.awardTitleCentre of Technology and Systems
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F00066%2F2020/PT
oaire.citation.conferenceDate2026
oaire.citation.conferencePlaceFrança
oaire.citation.titleProceedings of SPIE (Conference Proceedings Series)
oaire.citation.volume14096
oaire.fundingStream6817 - DCRRNI ID
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameVieira
person.familyNamePacheco
person.familyNameAlegria
person.familyNameFantoni
person.givenNameManuela
person.givenNameRita
person.givenNameElisabete
person.givenNameAlessandro
person.identifier10792
person.identifier1022927
person.identifier863202
person.identifier.ciencia-id9516-E25E-BB8E
person.identifier.ciencia-id9F13-D310-B5A3
person.identifier.ciencia-id8C1F-851A-9F1C
person.identifier.ciencia-id241E-E87C-552F
person.identifier.orcid0000-0002-1150-9895
person.identifier.orcid0000-0001-5192-3006
person.identifier.orcid0000-0003-4060-1057
person.identifier.orcid0000-0002-9938-0351
person.identifier.ridV-7860-2017
person.identifier.ridC-3062-2012
person.identifier.ridE-9945-2012
person.identifier.ridK-1105-2016
person.identifier.scopus-author-id7202140173
person.identifier.scopus-author-id8853708300
person.identifier.scopus-author-id8315848300
person.identifier.scopus-author-id7006535604
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
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ISEL - Eng. Quim. Biol. - Comunicações