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Micronutrients intake associated with DNA damage assessed by in a human biomonitoring study

2015-09Conference object Open access
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dc.contributor.authorLadeira, Carina
dc.contributor.authorViegas, Susana
dc.contributor.authorCarolino, Elisabete
dc.contributor.authorGomes, Manuel C.
dc.contributor.authorBrito, Miguel
dc.date.accessioned2015-09-04T15:41:13Z
dc.date.available2015-09-04T15:41:13Z
dc.date.issued2015-09
dc.description.abstractNutrition science has evolved into a multidisciplinary field that applies molecular biology and integrates individual health with the epidemiologic investigation of population health. Nutritional genomics studies the functional interaction of food and its components, macro and micronutrients, with the genome at the molecular, cellular, and systemic level. Diet can influence cancer development in several ways, namely direct action of carcinogens in food that can damage DNA, diet components (macro or micronutrients) that can block or induce enzymes involved in activation or deactivation of carcinogenic substances. Moreover, inadequate intake of some molecules involved in DNA synthesis, repair or methylation can influence mutation rate or changes in gene expression. Several studies support the idea that diet can influence the risk of cancer; however information concerning the precise dietary factor that determines human cancer is an ongoing debate. A lot of epidemiological studies, involving food frequency questionnaires, have been developed providing important information concerning diet and cancer, however, diet is a complex composite of various nutrients (macro and micronutrients) and non-nutritive food constituents that makes the search for specific factors almost limitless.por
dc.identifier.citationLadeira C, Viegas S, Carolino E, Gomes MC, Brito M. Micronutrients intake associated with DNA damage assessed by in a human biomonitoring study. In ICAW 2015 – 11th International Comet Assay Workshop, Antwerpen, Belgium, 1st to 4th September 2015.por
dc.identifier.doi10.3389/conf.fgene.2015.01.00012
dc.identifier.urihttp://hdl.handle.net/10400.21/5055
dc.language.isoengpor
dc.peerreviewedyespor
dc.relation.publisherversionhttp://www.frontiersin.org/10.3389/conf.fgene.2015.01.00012/event_abstractpor
dc.subjectComet assaypor
dc.subjectDNA damagepor
dc.subjectMicronutrientspor
dc.subjectHuman biomonitoringpor
dc.subjectOxidative damagepor
dc.titleMicronutrients intake associated with DNA damage assessed by in a human biomonitoring studypor
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceAntuérpiapor
person.familyNameLadeira
person.familyNameViegas
person.familyNameCarolino
person.familyNameBrito
person.givenNameCarina
person.givenNameSusana
person.givenNameElisabete
person.givenNameMiguel
person.identifier144237
person.identifier248817
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person.identifier.orcid0000-0001-6394-658X
person.identifier.ridJ-2572-2012
person.identifier.ridI-4053-2012
person.identifier.ridF-1012-2015
person.identifier.ridA-7970-2016
person.identifier.scopus-author-id36463788000
person.identifier.scopus-author-id35270591500
person.identifier.scopus-author-id25821697000
person.identifier.scopus-author-id35224551000
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
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