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Chronic airflow obstruction and ambient particulate air pollution

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Smoking is the most well-established cause of chronic airflow obstruction (CAO) but particulate air pollution and poverty have also been implicated. We regressed the sex-specific prevalence of CAO from 41 Burden of Obstructive Lung Disease study sites against smoking prevalence from the same study, the gross national income per capita, and the local annual mean level of ambient particulate matter (PM2.5) using negative binomial regression. The prevalence of CAO was not independently associated with PM2.5 but was strongly associated with smoking and was also associated with poverty. Strengthening tobacco control and improving understanding of the link between CAO and poverty should be prioritized.

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Chronic obstructive pulmonary disease Epidemiology Environmental exposure Air pollutants Air pollution Dust Particulate matter Chronic airflow obstruction

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Amaral AF, Burney PG, Patel J, Minelli C, Mejza F, Mannino DM, et al; BOLD Collaborative Research Group [Dias HB]. Chronic airflow obstruction and ambient particulate air pollution. Thorax. 2021;76(12):1236-41.

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