A STR mutation in a heteropaternal twin case

Geada, Helena; Ribeiro, Teresa; Brito, Miguel; Espinheira, Rosa; Rolf, Burkhard; Hohoff, Carsten; Brinkmann, Bernd

http://hdl.handle.net/10400.21/3367

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Abstract(s)

A heteropaternal male twin case with two men being alleged fathers was investigated as requested by the Court. Up to 37 PCR-based polymorphic DNA systems were studied in this case which was complicated by a paternal ACTBP2 mutation detected in one twin. This is the first report on a STR mutation in a double paternity case where both biological fathers were indisputably identified. The STR systems enable the resolution of these complex genetic relationships even in a case where a mutation in one STR locus was encountered.

Keywords

Paternity investigation Heteropaternal twins Minisatellites Short tandem repeats ACTBP2 mutation

URI

http://hdl.handle.net/10400.21/3367

Citation

Geada H, Ribeiro T, Brito M, Espinheira R, Rolf B, Hohoff C, et al. A STR mutation in a heteropaternal twin case. Forensic Sci Int. 2001;123(2-3):239-42.