Loading...
4 results
Search Results
Now showing 1 - 4 of 4
- LoBEMS-IoT for building and energy management systemsPublication . Mataloto, Bruno; Ferreira, Joao; Cruz, NunoThis work presents the efforts on optimizing energy consumption by deploying an energy management system using the current IoT component/system/platform integration trends through a layered architecture. LoBEMS (LoRa Building and Energy Management System), the proposed platform, was built with the mindset of proving a common platform that would integrate multiple vendor locked-in systems together with custom sensor devices, providing critical data in order to improve overall building efficiency. The actions that led to the energy savings were implemented with a ruleset that would control the already installed air conditioning and lighting control systems. This approach was validated in a kindergarten school during a three-year period, resulting in a publicly available dataset that is useful for future and related research. The sensors that feed environmental data to the custom energy management system are composed by a set of battery operated sensors tied to a System on Chip with a LoRa communication interface. These sensors acquire environmental data such as temperature, humidity, luminosity, air quality but also motion. An already existing energy monitoring solution was also integrated. This flexible approach can easily be deployed to any building facility, including buildings with existing solutions, without requiring any remote automation facilities. The platform includes data visualization templates that create an overall dashboard, allowing management to identify actions that lead to savings using a set of pre-defined actions or even a manual mode if desired. The integration of the multiple systems (air-conditioning, lighting and energy monitoring) is a key differentiator of the proposed solution, especially when the top energy consumers for modern buildings are cooling and heating systems. As an outcome, the evaluation of the proposed platform resulted in a 20% energy saving based on these combined energy saving actions.
- Comparative efficacy and safety of pharmacological interventions for managing sickle cell disease complications in children and adolescents: a systematic review with network meta-analysesPublication . Tonin, Fernanda; Ginete, Catarina; Ferreira, Joao; Delgadinho, Mariana; Fernandez-Llimos, Fernando; Brito, MiguelObjectives: Sickle cell disease (SCD), an inherited hemoglobinopathy that causes anemia, severe pain, and vaso-occlusive crisis (VOC), is currently recognized as a global public health concern, being the leading cause of pediatric stroke. Our aim was to synthesize the evidence on the efficacy and safety of interventions for managing SCD in this population. Methods: A systematic review with searches in PubMed, Scopus, and Web of Science was performed (April-2022). Randomized controlled trials comparing disease-modifying agents in SCD patients under 18 years old were included. For each outcome of interest, data were pooled by means of Bayesian network meta-analyses with the surface under the cumulative ranking curve analyses (SUCRA). Results were reported as odds ratio (OR) with 95% credibility intervals (CrI). Results: Seventeen trials (1982-2022) mostly from African countries (65%) and North America (53%), assessing the effect of different interventions’ regimens (hydroxyurea [n=6 trials], L-arginine [n=3], antiplatelets [n=2], immunotherapy/monoclonal antibodies [n=2], sulfates [n=2], docosahexaenoic acid [n=1], niprisan [n=1]) and placebo were included. No statistical differences among treatments were found for the main outcomes. SUCRA revealed that immunotherapy/monoclonal antibodies and hydroxyurea 20 mg/kg are potentially more effective against acute chest syndrome (83% and 76% probabilities, respectively), VOC (71% and 80%, respectively) and needing of transfusions (72% and 75%, respectively), while L-arginine (100-200 mg/kg) and placebo were more prone to these events. Although therapies were overall considered safe, antiplatelet and sulfates may lead to more discontinuations and severe adverse events (uncertainty evidence). Results were similar between age subgroups (<10 years vs. 10-19 years). Conclusions: The available evidence on the effect of drugs on managing SCD in children and adolescents is insufficient and weak. No clear definition for some outcomes exists. Hydroxyurea may remain the standard of care for this population, however, long-term well-designed, and well-reported trials comparing new immunotherapy/monoclonal antibodies should be performed.
- Die surface designer systemPublication . Ferreira, JoaoThis paper defines Die Surface Designer (DSD) System for fast draw die in the product development feasibility phase on surfaces coming from styling. We propose a CAD integration, for better support the design process in industry, particularly on the development of new products in automotive sector. The DSD system intends to reduce the lead time by providing and integrating flexible and efficient capabilities for testing early concepts from surface analysis points of view in automotive product development.
- MDAI: Model based design in automobile industryPublication . Ferreira, JoaoIt is proposed a new approach based on a methodology, assisted by a tool, to create new products in the automobile industry based on previous defined processes and experiences inspired on a set of best practices or principles: it is based on high-level models or specifications; it is component-based architecture centric; it is based on generative programming techniques. This approach follows in essence the MDA (Model Driven Architecture) philosophy with some specific characteristics. We propose a repository that keeps related information, such as models, applications, design information, generated artifacts and even information concerning the development process itself (e.g., generation steps, tests and integration milestones). Generically, this methodology receives the users' requirements to a new product (e.g., functional, non-functional, product specification) as its main inputs and produces a set of artifacts (e.g., design parts, process validation output) as its main output, that will be integrated in the engineer design tool (e.g. CAD system) facilitating the work.