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  • Sarcopenia and malnutrition in elderly admitted to hospital
    Publication . Dias, Ana; Monteiro, Catarina; Mendes, Diana; Cebola, Marisa; Carolino, Elisabete; Mendes, Lino; Rico, Miguel; Guerreiro, António
    Introduction: Sarcopenia is a progressive and generalized skeletal muscle disorder. The sarcopenia phenotype is also associated with malnutrition, regardless of whether the malnourished condition is rooted in low dietary intake, reduced nutrient bioavailability or high nutrient requirements. Aims: Relating sarcopenia with malnutrition. Materials and Methods: Cross-sectional study, developed at a central hospital, between April and July 2019. Elderly people (≥ 70 years) admitted to internal medicine service with the capacity to make their informed consent, without the intervention of any element of coercion were admitted to the study. Sarcopenia was assessed through the European Working Group on Sarcopenia criteria in Older People (EWGSOP), which include the evaluation of the grip strength (GS), appendicular skeletal muscle mass (ASM) predicted by bioelectrical impedance analysis and physical performance (gait speed). The risk of malnutrition was assessed according to the Mini Nutrition Assessment - MNA® Elderly. Results: n=32 patients, with a mean age of 79.7 + 5.9 years (70-91). At hospital admission 93.8% (n=30) were sarcopenic, 100% (n=30) presented low GS, 75% (n=24) had low ASMM and 3.1% (n=1) had normal gait speed. According to the MNA® short form, 59% (n=19) had a nutritional risk and of that group, 68% (n=13) were at risk of malnutrition and 16% (n=3) were malnourish after completing the MNA® long-form, both also had a diagnostic of sarcopenia. However, there were no significant correlations between the MNA® and the sarcopenia evaluation criteria. Discussion/Conclusion: In a population of geriatric inpatients, subjects with malnutrition risk and sarcopenia are at increased risk of long-term all-cause mortality compared to subjects with either malnutrition/malnutrition risk or sarcopenia. Therefore, the malnutrition-sarcopenia syndrome may serve as an important prognostic factor in the management of hospitalized older patients.
  • Sarcopenia and risk of fall in elderly admitted to hospital
    Publication . Monteiro, Catarina; Mendes, Diana; Cebola, Marisa; Carolino, Elisabete; Mendes, Lino; Rico, Miguel Toscano; Guerreiro, António
    Introduction: Sarcopenia, a progressive and widespread disease of the skeletal muscle, has been a topic of interest. This age-related disease is known to be highly associated with disability, functional decline, frailty and falls. Aims: Relating sarcopenia with the risk of falls. Materials and Methods: Cross-sectional study, developed in Lisbon, in the period from April 22 to July 5, 2019. Elderly people (≥ 70 years) admitted to a hospital institution (up to 72 hours) with the capacity to make their informed consent, without the intervention of any element of coercion, with enough knowledge of the aims of the study that allowed free and informed decision making were admitted to the study. Sarcopenia was assessed through the European Working Group on Sarcopenia criteria in Older People 2 (EWGSOP2), which include the evaluation of the grip strength (GS), appendicular skeletal muscle mass (ASMM) predicted by bioelectrical impedance analysis and physical performance (gait speed). The risk of falls was assessed according to the Morse Scale. Results: n=32 patients, with a mean age of 79.7 + 5.9 years (70-91). At hospital admission 93.8% (n=30) were sarcopenic, 100% (n=30) presented low GS, 75% (n=24) had low ASMM and 3.1% (n=1) had normal gait speed. There was no significant correlation between the Morse Scale and the GS (r=-0.471; p=0,056) and the ASMM (r=0,017; p=0,948). There was a significant correlation between the gait speed test and the Morse Scale (r =-0.689; p=0.002). Patients with gait difficulties are at increased risk of falling. Discussion/Conclusion: The sarcopenia and risk of fall assessment are extremely relevant at hospital admission. It demonstrates the need to establish protocols to evaluate the mentioned parameters of the algorithm and to intervene in this population since the factors that constitute the algorithm proposed by EWGSOP2 tend to worsen during hospitalization.
  • Association between whey protein, regional fat mass, and strength in resistance-trained men: a cross-sectional study
    Publication . Batista, Ana; Monteiro, Cristina P.; Borrego, Rute; Matias, Catarina N.; Teixeira, Filipe J.; Valamatos, Maria J.; Oliveira, Ana C.; Reis, Joana F.; Mendes, Lino; Sardinha, Luís B.
    The purpose of this study was to evaluate the association between whey protein supplementation, body composition, and muscle strength in resistance-trained individuals. Forty-nine healthy males, aged 18 to 35 years and were engaged in resistance training for at least 1 year, were assigned into 2 groups according to whey protein intake (whey - n = 26, age: 30.7 ± 7.4 years, body mass: 75.8 ± 9.0 kg; without whey: n = 23, age: 31.0 ± 7.4 years, body mass: 77.9 ± 9.3 kg). Using a cross-sectional design, a morning assessment of body fat mass (FM) (by dual-energy X-ray absorptiometry) and strength (using 1-repetition maximum for bench press and back squat) was performed. Nutritional assessment was performed by 3-day food records. Regarding nutritional habits, differences between total energy intake (kcal) and estimated energy requirements (kcal) were observed. Results, from raw data or controlling for energy intake, estimated energy requirements, or achieved percentage of energy requirements, showed that whey protein supplementation was inversely correlated with whole-body FM (R = -0.367 (p = 0.010); R = -0.317 (p = 0.049); R = -0.380 (p = 0.011); R = -0.321 (p = 0.047), respectively), trunk FM (R = -0.396 (p = 0.005), R = -0.367 (p = 0.022), R = -0.423 (p = 0.004), R = -0.369 (p = 0.021), respectively) and android FM (R = -0.381 (p = 0.007), R = -0.332 (p = 0.039), R = -0.383 (p = 0.010), R = -0.336 (p = 0.036), respectively). No correlations were found between muscle strength outcomes and whey protein supplementation. The present data suggest that whey protein ingestion has a positive association with whole-body and regional (trunk and android) FM.