Browsing by Author "Matos, Catarina"
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- Adaptação do posto escolar em pacientes com baixa visãoPublication . Ramos, Diana; Matos, Catarina; Fernandes, Nádia; Poças, IldaA grande maioria das crianças e jovens com baixa visão podem frequentar a escola comum, no entanto impõe-se a necessidade de se proceder a adaptações definidas com base numa rigorosa avaliação do funcionamento visual que permita minimizar as barreiras do meio escolar. 1. Objectivos - Definir estratégias de gestão e organização da escola e sala de aula, descrever normas de acessibilidade gráfica e prescrição de tecnologias de apoio, mais adequadas para adaptação do posto escolar. 2. Metodologia - Identificar procedimentos adequados através de revisão bibliográfica, com análise de artigos e livros, por pesquisa nos bancos de dados da B-on, Koha, Zotero, Pubmed (MEDLINE) e LILACS. 3. Resultados - A adaptação do meio escolar tem como objetivo facilitar a inclusão do aluno com deficiência visual na comunidade escolar, de modo a reduzir os problemas inerentes às suas limitações. Desta forma, a adaptação passa por estratégias de gestão e organização da escola e sala de aula que devem ser utilizadas pelo professor, bem como, pela elaboração de materiais em formato impresso adequados, e prescrição de tecnologias de apoio, com objetivo de promover a participação destes alunos. As estratégias de gestão e organização da escola/sala de aula consistem em alterações ambientais, ergonómicas e espaciais. As tecnologias de apoio podem ser adaptadas ao aluno de acordo com a avaliação funcional do mesmo e posterior treino de utilização. 4. Discussão / Conclusão - O resultado da avaliação funcional deve conduzir a uma prescrição de tecnologias de apoio que ajudarão o aluno a ser mais autónomo e a desempenhar com menor dificuldade atividades diárias e tarefas escolares, minorando as barreiras que se colocam à sua aprendizagem e participação, tornando-os futuramente em elementos activos da sociedade.
- Adaptação do posto laboral em indivíduos com baixa visãoPublication . Matos, Catarina; Ramos, Diana; Fernandes, Nádia; Poças, IldaO indivíduo portador de baixa visão, sendo um individuo social e profissionalmente activo, impõe-se a necessidade de adaptação do posto laboral, não só em modificações ambientais, espaciais e ergonómicas do local de trabalho como também na aquisição de equipamentos adequados que permitem ao indivíduo aumentar o seu rendimento. 1. Objectivos - Definir estratégias de organização e adaptação do posto de trabalho, para indivíduos de baixa visão. Descrever procedimentos adequados às capacidades visuais de cada individuo, interligadas com as condições ergonómicas e a actividade diária. 2. Metodologia - Identificar procedimentos adequados através de revisão bibliográfica, com análise de artigos e livros, por pesquisa nos bancos de dados da B-on, Koha, Zotero, Pubmed (MEDLINE) e LILACS. 3. Resultados - A adaptação do posto laboral consiste não só em modificações ambientais, espaciais e ergonómicas do local de trabalho como também na aquisição de equipamentos adequados que permitam ao individuo aumentar o seu rendimento. Para se proceder à adaptação do posto de trabalho é necessário avaliar as funções visuais do individuo, bem como as suas necessidades/dificuldades e objetivos. Para além disso, deve-se ter em conta a profissão do paciente, a descrição da sua atividade laboral, e o levantamento das exigências visuais no local de trabalho. Isto consiste na recolha das características de iluminação, distância de trabalho, contraste, localização dos objetos, tipo de material impresso utilizado, restantes condições ergonómicas e introdução de diferentes tecnologias de apoio. 4. Discussão / Conclusão - Com a adaptação do posto laboral, o indivíduo deve conseguir realizar as suas tarefas profissionais com menor dificuldade e maior eficácia, utilizando as tecnologias de apoio adequadas e as condições ambientais recomendadas. Pretende-se que o paciente consiga através das mesmas, aumentar tanto a produtividade como o seu rendimento, sendo capaz de realizar as suas responsabilidades laborais de forma atempada e eficaz, minorando barreiras decorrentes das suas limitações.
- An active seismic zone in intraplate West Iberia inferred from high-resolution geophysical dataPublication . Custodio, Susana; Batlló, Josep; Zahradnik, Jiri; Arroucau, Pierre; Silveira, Graça; Heimann, Sebastian; Matos, CatarinaIntraplate Iberia is a region of slow lithopsheric deformation (<1mm/yr) with significant historical earthquake activity. Recent high-quality instrumental data have shown that small-magnitude earthquakes collapse along clusters and lineaments, which however do not bear a clear relationship to geologically mapped active structures. In this article, we investigate the controls of these earthquake clusters. In particular, we study two of the identified clustersthe Arraiolos and the Evora seismic zones (ASZ and ESZ), located in the Western Ossa Morena Zone, southwest Iberia. The ASZ marks a sharp boundary between a seismically active region to its south and a more quiet region to its north. We revise historical earthquakes in order to clarify whether earthquake activity in the region is persistent. We use data from a local network to compute accurate epicenters, focal depth, focal mechanisms, and spatiotemporal clustering, thus characterizing ongoing small-scale fracturing. Finally, we analyze complementary data sets, including tomographic models, Global Navigation Satellite Systems data, magnetic anomalies, and gravity anomalies, in order to discuss the factors that control seismogenesis in the two seismic zones. Consistency between earthquake locations, focal mechanisms and Global Navigation Satellite Systems data suggests that the ASZ is an active right-lateral shear zone, which divides two blocks within the Western Ossa Morena Zone. The ESZ seems to localize microseismicity due to its granitic lithology. These results suggest that high-resolution geophysical data have the potential to reveal blocks with different seismogenic and rheological behaviors, which may be used to improve our understanding of fault systems and the assessment of earthquake hazard in slowly deforming regions. Plain Language Summary Mainland Portugal is a region of slow lithospheric deformation. This means that changes in Earth's outmost layerthe lithosphereoccur at very low rates (<1mm/yr). In such environments, faults producing earthquakes are not easy to identify at the Earth's surface, both because their evidence can be gradually erased by wind and water or simply because they do not reach the surface. Recent studies have shown that small earthquakes in mainland Portugal group together delineating seismically more active regions. In this article we focus in two particular groups of earthquakesthe Arraiolos and the Evora seismic zones (ASZ and ESZ) and we investigate why they occur in these particular locations. We obtain precise maps of earthquake epicenters. When possible, we also analyze the direction of slip during the earthquake and the orientation of the fracture on which it occurred. We compare our results with other data sets, such as images of the Earth's interior, that could give hints about the constitution of crust beneath the ASZ and the ESZ. Earthquakes epicenters show fault sections at depth in the ASZ. These faults separate two crustal blocks with distinct material properties. In the ESZ earthquakes are associated to contrasts in crustal materials.
- Educating for earthquake science and risk in a tectonically slowly deforming regionPublication . Custódio, Susana; Silveira, Graça; Matias, Luís; Mata, Isabel; Matos, Catarina; Palma-Oliveira, José Manuel; Rocha, Francisco; Lopes, Fernando C.Over the past decade, scientists have been called to participate more actively in public education and outreach (E&O). This is particularly true in fields of significant societal impact, such as earthquake science. Local earthquake risk culture plays a role in the way that the public engages in educational efforts. In this article, we describe an adapted E&O program for earthquake science and risk. The program is tailored for a region of slow tectonic deformation, where large earthquakes are extreme events that occur with long return periods. The adapted program has two main goals: (1) to increase the awareness and preparedness of the population to earthquake and related risks (tsunami, liquefaction, fires, etc.), and (2) to increase the quality of earthquake science education, so as to attract talented students to geosciences. Our integrated program relies on activities tuned for different population groups who have diferente interests and abilities, namely young children, teenagers, young adults, and professionals.
- Educating for earthquake science and risk in a tectonically slowly deforming regionPublication . Custódio, Susana; Silveira, Graça; Matias, Luis; Mata, Isabel; Matos, Catarina; Palma‐Oliveira, José Manuel; Rocha, Francisco; Lopes, Fernando C.Over the past decade, scientists have been called to participate more actively in public education and outreach (E&O). This is particularly true in fields of significant societal impact, such as earthquake science. Local earthquake risk culture plays a role in the way that the public engages in educational efforts. In this article, we describe an adapted E&O program for earthquake science and risk. The program is tailored for a region of slow tectonic deformation, where large earthquakes are extreme events that occur with long return periods. The adapted program has two main goals: (1) to increase the awareness and preparedness of the population to earthquake and related risks (tsunami, liquefaction, fires, etc.), and (2) to increase the quality of earthquake science education, so as to attract talented students to geosciences. Our integrated program relies on activities tuned for different population groups who have different interests and abilities, namely young children, teenagers, young adults, and professionals.
- From cilia to cancer: the two splicing variants of the human TBCCD1 genePublication . Carmona, Bruno; Justino, Gonçalo; Matos, Catarina; Pádua, Mário; Nolasco, Sofia; Marinho, Susana H.; Soares, HelenaAlmost all human genes that contain multiple exons undergo alternative splicing. Therefore, a single gene can originate multiple mRNA isoforms which causes a dramatic increase in the variability of the expected proteome. Noteworthy, phenotypic variability and disease susceptibility in human populations are related to alternative splicing. Published work from our group identified a new human centrosomal protein, TBCC domain-containing 1 (TBCCD1). Our studies revealed that this gene undergoes alternative splicing producing at least two transcripts encoding proteins. Here we analyze the differential functions of the two splicing variants (TBCCD1v1 and TBCCD1v2). Both variants present distinct cellular localization being TBCCD1v1 essentially centrosomal, whereas TBCCD1v2 is cytoplasmatic. The screening for TBCCD1v2 proximity interactome using BioID identified 19 proteins that functionally group in kinetochore, MT/cilia, and DNA-binding proteins. Striking, the overexpression of TBCCD1v2 decreases the levels of the kinetochore protein CENP-M, a protein upregulated in tumors. On the other hand, the TBCCD1v1 is involved in MT organization and is required to maintain the distal structure of the mother centriole. Our BioID screening for TBCCD1v1 interactors revealed 82 distinct proteins including several well-known proteins encoded by ciliopathy genes. A wider analysis of how TBCCD1v1 levels impact cellular physiological proteome showed that the group of proteins presenting fold changes in their levels vs control cells is enriched in proteins involved in focal adhesions, namely HSPA5/GRP-78/BiP, PDIA3, RPS10, MSN, TGM2, and PPP1R12A. Together our results show that we are still far from having a complete picture of the functional importance of TBCCD1 and how its deregulation may be associated not only with the development of ciliopathies but also with more common diseases like cancer.
- Upper crustal structure of Madeira Island revealed from ambient noise tomographyPublication . Matos, Catarina; Silveira, Graça; Matias, Luís; Caldeira, Rita; Ribeiro, M. Luísa; Dias, Nuno; Krüger, Frank; Santos, Telmo Bento dosWe present the first image of the Madeira upper crustal structure, using ambient seismic noise tomography. 16 months of ambient noise, recorded in a dense network of 26 seismometers deployed across Madeira, allowed reconstructing Rayleigh wave Green's functions between receivers. Dispersion analysis was performed in the short period band from 1.0 to 4.0 s. Group velocity measurements were regionalized to obtain 20 tomographic images, with a lateral resolution of 2.0 km in central Madeira. Afterwards, the dispersion curves, extracted from each cell of the 2D group velocity maps, were inverted as a function of depth to obtain a 3D shear wave velocity model of the upper crust, from the surface to a depth of 2.0 km. The obtained 3D velocity model reveals features throughout the island that correlates well with surface geology and island evolution. (C) 2015 Elsevier B.V. All rights reserved.
- Upper crustal structure of Madeira Island revealed from ambient noise tomographyPublication . Matos, Catarina; Silveira, Graça; Matias, Luís; Caldeira, Rita; Ribeiro, M. Luísa; Dias, Nuno; Krüger, Frank; Santos, Telmo Bento dosWe present the first image of the Madeira upper crustal structure, using ambient seismic noise tomography. 16 months of ambient noise, recorded in a dense network of 26 seismometers deployed across Madeira, allowed reconstructing Rayleigh wave Green's functions between receivers. Dispersion analysis was performed in the short period band from 1.0 to 4.0 s. Group velocity measurements were regionalized to obtain 20 tomographic images, with a lateral resolution of 2.0 km in central Madeira. Afterwards, the dispersion curves, extracted from each cell of the 2D group velocity maps, were inverted as a function of depth to obtain a 3D shear wave velocity model of the upper crust, from the surface to a depth of 2.0 km. The obtained 3D velocity model reveals features throughout the island that correlates well with surface geology and island evolution. (C) 2015 Elsevier B.V. All rights reserved.