Browsing by Author "Bellido, J."
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- The recycling of tubulin heterodimer by tubulin cofactors TBCA, TBCB, and TBCE is blocked by colchicinePublication . Nolasco, Sofia; Bellido, J.; Serna, M.; Carmona, Bruno; Soares, Helena; Zabala, J.Colchicine has been used to treat gout and effectively prevent autoinflammatory diseases and primary and recurrent pericarditis episodes. The anti-inflammatory action of colchicine seems to result from compromised microtubule (MT) networks that affect several inflammatory pathways in cells that mediate immune response like the entire NLRP3 inflammasome.