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Browsing by Author "Al Ghobain, M."

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  • Association between lung function and dyspnoea and its variation in the multinational Burden of Obstructive Lung Disease (BOLD) study
    Publication . Müller, A.; Wouters, E. F.; Koul, P.; Welte, T.; Harrabi, I.; Rashid, A.; Loh, L. C.; Al Ghobain, M.; Elsony, A.; Ahmed, R.; Potts, J.; Mortimer, K.; Rodrigues, F.; Paraguas, S. N.; Juvekar, S.; Agarwal, D.; Obaseki, D.; Gislason, T.; Seemungal, T.; Nafees, A. A.; Jenkins, C.; Dias, Hermínia Brites; Franssen, F. M.; Studnicka, M.; Janson, C.; Cherkaski, H. H.; El Biaze, M.; Mahesh, P. A.; Cardoso, João; Burney, P.; Hartl, S.; Janssen, D. J.; Amaral, A. F.
    Background: Dyspnoea is a common symptom of respiratory disease. However, data on its prevalence in general populations and its association with lung function are limited and are mainly from high-income countries. This study aimed to estimate the prevalence of dyspnoea across several world regions and to investigate the association of dyspnoea with lung function. Methods: Dyspnoea was assessed, and lung function was measured in 25,806 adult participants of the multinational Burden of Obstructive Lung Disease study. Dyspnoea was defined as ≥2 on the modified Medical Research Council (mMRC) dyspnoea scale. The prevalence of dyspnoea was estimated for each of the study sites and compared across countries and world regions. Multivariable logistic regression was used to assess the association of dyspnoea with lung function in each site. Results were then pooled using random-effects meta-analysis. Results: The prevalence of dyspnoea varied widely across sites without a clear geographical pattern. The mean prevalence of dyspnoea was 13.7 % (SD=8.2 %), ranging from 0 % in Mysore (India) to 28.8 % in Nampicuan-Talugtug (Philippines). Dyspnoea was strongly associated with both spirometry restriction (FVC
    2024-04Journal article Open access Show more
  • Prevalence of chronic cough, its risk factors and population attributable risk in the Burden of Obstructive Lung Disease (BOLD) study: a multinational cross-sectional study
    Publication . Abozid, Hazim; Patel, Jaymini; Burney, Peter; Hartl, Sylvia; Breyer-Kohansal, Robab; Mortimer, Kevin; Nafees, Asaad A.; Al Ghobain, Mohammed; Welte, Tobias; Harrabi, Imed; Denguezli, Meriam; Loh, Li Cher; Rashid, Abdul; Gislason, Thorarinn; Barbara, Cristina; Cardoso, Joao; Rodrigues, Fatima; Seemungal, Terence; Obaseki, Daniel; Juvekar, Sanjay; Paraguas, Stefanni Nonna; Tan, Wan C.; Franssen, Frits M.E.; Mejza, Filip; Mannino, David; Janson, Christer; Cherkaski, Hamid Hacene; Anand, Mahesh Padukudru; Hafizi, Hasan; Buist, Sonia; Koul, Parvaiz A.; El Sony, Asma; Breyer, Marie-Kathrin; Burghuber, Otto C.; Wouters, Emiel F.M.; Amaral, Andre F.S.; Hafizi, Hasan; Aliko, Anila; Bardhi, Donika; Tafa, Holta; Thanasi, Natasha; Mezini, Arian; Teferici, Alma; Todri, Dafina; Nikolla, Jolanda; Kazasi, Rezarta; Cherkaski, Hamid Hacene; Bengrait, Amira; Haddad, Tabarek; Zgaoula, Ibtissem; Ghit, Maamar; Roubhia, Abdelhamid; Boudra, Soumaya; Atoui, Feryal; Yakoubi, Randa; Benali, Rachid; Bencheikh, Abdelghani; Ait-Khaled, Nadia; Jenkins, Christine; Marks, Guy; Bird, Tessa; Espinel, Paola; Hardaker, Kate; Toelle, Brett; Studnicka, Michael; Dawes, Torkil; Lamprecht, Bernd; Schirhofer, Lea; Islam, Akramul; Ahmed, Syed Masud; Islam, Shayla; Islam, Qazi Shafayetul; Mesbah-Ul-Haque, null; Chowdhury, Tridib Roy; Chatterjee, Sukantha Kumar; Mia, Dulal; Chandra Das, Shyamal; Rahman, Mizanur; Islam, Nazrul; Uddin, Shahaz; Islam, Nurul; Khatun, Luiza; Parvin, Monira; Khan, Abdul Awal; Islam, Maidul; Lawin, Herve; Kpangon, Arsene; Kpossou, Karl; Agodokpessi, Gildas; Ayelo, Paul; Fayomi, Benjamin; Mbatchou, Bertrand; Ashu, Atongno Humphrey; Tan, Wan C.; Wang, Wen; Zhong, NanShan; Liu, Shengming; Lu, Jiachun; Ran, Pixin; Wang, Dali; Zheng, Jin-ping; Zhou, Yumin; Jogi, Rain; Laja, Hendrik; Ulst, Katrin; Zobel, Vappu; Lill, Toomas-Julius; Adegnika, Ayola Akim; Welte, Tobias; Bodemann, Isabelle; Geldmacher, Henning; SchwedaLinow, Alexandra; Gislason, Thorarinn; Benedikdtsdottir, Bryndis; Jorundsdottir, Kristin; Lovisa Gudmundsdottir, null; Gudmundsdottir, Sigrun; Gudmundsson, Gunnar; Rao, Mahesh; Koul, Parvaiz A.; Malik, Sajjad; Hakim, Nissar A.; Khan, Umar Hafiz; Chowgule, Rohini; Shetye, Vasant; Raphael, Jonelle; Almeda, Rosel; Tawde, Mahesh; Tadvi, Rafiq; Katkar, Sunil; Kadam, Milind; Dhanawade, Rupesh; Ghurup, Umesh; Juvekar, Sanjay; Hirve, Siddhi; Sambhudas, Somnath; Chaidhary, Bharat; Tambe, Meera; Pingale, Savita; Umap, Arati; Umap, Archana; Shelar, Nitin; Devchakke, Sampada; Chaudhary, Sharda; Bondre, Suvarna; Walke, Savita; Gawhane, Ashleshsa; Sapkal, Anil; Argade, Rupali; Gaikwad, Vijay; Salvi, Sundeep; Brashier, Bill; Londhe, Jyoti; Madas, Sapna; Aquart-Stewart, Althea; Aikman, Akosua Francia; Sooronbaev, Talant M.; Estebesova, Bermet M.; Akmatalieva, Meerim; Usenbaeva, Saadat; Kydyrova, Jypara; Bostonova, Eliza; Sheraliev, Ulan; Marajapov, Nuridin; Toktogulova, Nurgul; Emilov, Berik; Azilova, Toktogul; Beishekeeva, Gulnara; Dononbaeva, Nasyikat; Tabyshova, Aijamal; Mortimer, Kevin; Nyapigoti, Wezzie; Mwangoka, Ernest; Kambwili, Mayamiko; Chipeta, Martha; Banda, Gloria; Mkandawire, Suzgo; Banda, Justice; Loh, Li-Cher; Rashid, Abdul; Sholehah, Siti; Benjelloun, Mohamed C.; Nejjari, Chakib; Elbiaze, Mohamed; El Rhazi, Karima; Wouters, E.F.M.; Wesseling, G.J.; Obaseki, Daniel; Erhabor, Gregory; Awopeju, Olayemi; Adewole, Olufemi; Gulsvik, Amund; Endresen, Tina; Svendsen, Lene; Nafees, Asaad A.; Irfan, Muhammad; Fatmi, Zafar; Zahidie, Aysha; Shaukat, Natasha; Iqbal, Meesha; Idolor, Luisito F.; Guia, Teresita S.; Francisco, Norberto A.; Roa, Camilo C.; Ayuyao, Fernando G.; Tady, Cecil Z.; Tan, Daniel T.; Banal-Yang, Sylvia; Balanag, Vincent M.; Reyes, Maria Teresita N.; Dantes, Renato B.; Dantes, Renato B.; Amarillo, Lourdes; Berratio, Lakan U.; Fernandez, Lenora C.; Francisco, Norberto A.; Garcia, Gerard S.; Idolor, Luisito F.; Naval, Sullian S.; Reyes, Thessa; Roa, Camilo C.; Sanchez, Flordeliza; Simpao, Leander P.; Nizankowska-Mogilnicka, Ewa; Frey, Jakub; Harat, Rafal; Mejza, Filip; Nastalek, Pawel; Pajak, Andrzej; Skucha, Wojciech; Szczeklik, Andrzej; Twardowska, Magda; Barbara, Cristina; Rodrigues, Fatima; Dias, Hermínia Brites; Cardoso, Joao; Almeida, João; Matos, Maria Joao; Simão, Paula; Santos, Moutinho; Ferreira, Reis; Al Ghobain, M.; Alorainy, H.; El-Hamad, E.; Al Hajjaj, M.; Hashi, A.; Dela, R.; Fanuncio, R.; Doloriel, E.; Marciano, I.; Safia, L.; Bateman, Eric; Jithoo, Anamika; Adams, Desiree; Barnes, Edward; Freeman, Jasper; Hayes, Anton; Hlengwa, Sipho; Johannisen, Christine; Koopman, Mariana; Louw, Innocentia; Ludick, Ina; Olckers, Alta; Ryck, Johanna; Storbeck, Janita; Gunasekera, Kirthi; Wickremasinghe, Rajitha; Elsony, Asma; Elsadig, Hana A.; Osman, Nada Bakery; Noory, Bandar Salah; Mohamed, Monjda Awad; Akasha Ahmed Osman, Hasab Alrasoul; Moham ed Elhassan, Namarig; El Zain, Abdel Mu’is; Mohamaden, Marwa Mohamed; Khalifa, Suhaiba; Elhadi, Mahmoud; Hassan, Mohand; Abdelmonam, Dalia; Janson, Christer; Olafsdottir, Inga Sif; Nisser, Katarina; SpetzNystrom, Ulrike; Hagg, Gunilla; Lund, GunMarie; Seemungal, Terence; Lutchmansingh, Fallon; Conyette, Liane; Harrabi, Imed; Denguezli, Myriam; Tabka, Zouhair; Daldoul, Hager; Boukheroufa, Zaki; Chouikha, Firas; Khalifa, Wahbi Belhaj; Kocabas, Ali; Hancioglu, Attila; Hanta, Ismail; Kuleci, Sedat; Turkyilmaz, Ahmet Sinan; Umut, Sema; Unalan, Turgay; Burney, Peter G.J.; Jithoo, Anamika; Gnatiuc, Louisa; Azar, Hadia; Patel, Jaymini; Amor, Caron; Potts, James; Tumilty, Michael; McLean, Fiona; Dudhaiya, Risha; Buist, A. Sonia; McBurnie, Mary Ann; Vollmer, William M.; Gillespie, Suzanne; Sullivan, Sean; Lee, Todd A.; Weiss, Kevin B.; Jensen, Robert L.; Crapo, Robert; Enright, Paul; Mannino, David M.; Cain, John; Copeland, Rebecca; Hazen, Dana; Methvin, Jennifer
    Background: Chronic cough is a common respiratory symptom with an impact on daily activities and quality of life. Global prevalence data are scarce and derive mainly from European and Asian countries and studies with outcomes other than chronic cough. In this study, we aimed to estimate the prevalence of chronic cough across a large number of study sites as well as to identify its main risk factors using a standardized protocol and definition. Methods: We analyzed cross-sectional data from 33,983 adults (≥40 years), recruited between Jan 2, 2003 and Dec 26, 2016, in 41 sites (34 countries) from the Burden of Obstructive Lung Disease (BOLD) study. We estimated the prevalence of chronic cough for each site accounting for sampling design. To identify risk factors, we conducted multivariable logistic regression analysis within each site and then pooled estimates using random-effects meta-analysis. We also calculated the population-attributable risk (PAR) associated with each of the identified risk factors. Findings: The prevalence of chronic cough varied from 3% in India (rural Pune) to 24% in the United States of America (Lexington, KY). Chronic cough was more common among females, both current and passive smokers, those working in a dusty job, those with a history of tuberculosis, those who were obese, those with a low level of education, and those with hypertension or airflow limitation. The most influential risk factors were current smoking and working in a dusty job. Interpretation: Our findings suggested that the prevalence of chronic cough varies widely across sites in different world regions. Cigarette smoking and exposure to dust in the workplace are its major risk factors.
    2024-02Journal article Open access Show more