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Non-invasive ECG recording for zebrafish

dc.contributor.authorVaz da Silva, V
dc.contributor.authorPatricia Napoleão
dc.contributor.authorGeraldes, Vera
dc.contributor.authorRocha, Isabel
dc.date.accessioned2018-02-26T12:11:48Z
dc.date.available2018-02-26T12:11:48Z
dc.date.issued2017-03-30
dc.description.abstractMyocardial infarction (MI) is a high prevalence cardiovascular disease with a tendency to increase. Although MI therapy has increased its effectiveness, the loss of myocardial function in consequence of MI is still responsible for major subsequent complications as rhythm changes and heart failure. In human hearts, MI is characterized by cardiomyocyte death and fibrin deposition, which is later replaced by scar tissue. In opposition, zebrafish heart undergoes minimal scaring and cardiac tissue can undergo full functionally regeneration in 60 to 120 days. Therefore, this animal model has been used in cardiovascular research as a model for studying mechanisms of cardiac regeneration. The hearts of zebrafish is anatomically different from the human heart, though the electrocardiogram (ECG) pattern and the critical conduction pathways are comparable to the human’s. The objective of our full project is the implementation of na ECG recording system with 3 orthogonal electrodes in 2 planes, in order to create a 4D recording of the zebrafish cardiac electrical activity. Here we present our preliminary work related to a non-invasive ECG monitoring with two electrodes.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSILVA, Vítor Vaz da; NAPOLEÃO, Patrícia; GERALDES, Vera; ROCHA, Isabel – Non-invasive ECG recording for zebrafish. In 2017 IEEE 5th Portuguese Meeting on Bioengineering (ENBENG). Coimbra, Portugal: IEEE, 2017. ISBN 978-1-5090-4802-1. Pp. 1-4.pt_PT
dc.identifier.doi10.1109/ENBENG.2017.7889468pt_PT
dc.identifier.isbn978-1-5090-4802-1
dc.identifier.isbn978-1-5090-4801-4
dc.identifier.urihttp://hdl.handle.net/10400.21/8136
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherInstitute of Electrical and Electronics Engineerspt_PT
dc.relationFCT - SFRM/BPD/6308/2009pt_PT
dc.relation.publisherversionhttp://ieeexplore.ieee.org/stamp/stamp.jsp?arnumber=7889468pt_PT
dc.subjectMyocardial infarction (MI)pt_PT
dc.subjectZebrafishpt_PT
dc.titleNon-invasive ECG recording for zebrafishpt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceCoimbra, Portugal - 16-18 Feb. 2017pt_PT
oaire.citation.endPage4pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.title2017 IEEE 5th Portuguese Meeting on Bioengineering (ENBENG)pt_PT
person.familyNameVaz da Silva
person.familyNameNapoleão
person.givenNameVitor
person.givenNamePatrícia
person.identifier.ciencia-idAB18-740E-B580
person.identifier.ciencia-idC11E-8BE9-A97F
person.identifier.orcid0000-0003-4265-6553
person.identifier.orcid0000-0002-5896-1440
person.identifier.scopus-author-id8872775500
rcaap.rightsclosedAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublicationbf73931d-fd0b-44bc-82a9-fdfd2157406f
relation.isAuthorOfPublication5e329a08-0816-4a72-a4b2-3a6c3cf457c9
relation.isAuthorOfPublication.latestForDiscovery5e329a08-0816-4a72-a4b2-3a6c3cf457c9

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