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Green synthesis of gold nanoparticles and their deposition on ITO surfaces

2021-03-05Conference object Restricted access
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dc.contributor.authorLapa, Hugo
dc.contributor.authorSilva, Nelson
dc.contributor.authorFantoni, Alessandro
dc.contributor.authorMaçarico, A. Filipe
dc.contributor.authorAlmeida, Gabriela
dc.contributor.authorAlegria, Elisabete
dc.date.accessioned2021-09-21T13:12:16Z
dc.date.available2021-09-21T13:12:16Z
dc.date.issued2021-03-05
dc.descriptionEste trabalho foi financiado pelo Concurso Anual para Projetos de Investigação, Desenvolvimento, Inovação e Criação Artística (IDI&CA) 2020 do Instituto Politécnico de Lisboa. Código de referência IPL/2020/AGE-SPReS/ISEL
dc.description.abstractThe use of plasmonic nanoparticles for biomedical applications has been widely explored, resulting in significant advances in the construction of optical biosensors. The shape and size of AuNPs determines the spectral signature of their Localized Surface Plasmon Resonance (LSPR) and, therefore, the features of their plasmonic band can be used to monitor surface changes such as those related to protein binding or nanoparticle aggregation. In this work, gold nanoparticles (AuNPs) were produced based on a green and sustainable methodology using tea leaves. The phytochemicals present in tea act as reducing and stabilizing agents. To optimize the AuNPs deposition (nanomaterial proximity, homogenization and substrate coverage), ITO surfaces were modified with different materials, namely sol-gel matrices (e.g. (3-aminopropyl) triethoxysilane (APTES)), cross-linking agents (e.g., glutaraldehyde) and biopolymers (e.g., Bovine Serum Albumin (BSA)). The produced AuNPs were deposited directly onto ITO surfaces functionalized with APTES or in a mixture of BSA and glutaraldehyde; these matrices are transparent and thus suitable for optical applications. The functionalization procedure of ITO surfaces with the referred materials was performed by two methodologies: i) direct deposition of the matrix solution using a micropipette and ii) ultrasound irradiation. The resulting functionalized ITO surfaces were compared and characterized by light transmission spectroscopy. Accordingly, the tea-AuNPs deposited in the presence of BSA and glutaraldehyde provided the best plasmonic response, being the most promising ones for the development of an optical immunosensor.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationLAPA, Hugo; [et al] – Green synthesis of gold nanoparticles and their deposition on ITO surfaces. Proceedings of SPIE – Colloidal Nanoparticles for Biomedical Applications XVI. Vol. 11659, (2021), pp. 116590Q-1 - 116590Q-9pt_PT
dc.identifier.doi10.1117/12.2582983pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.21/13769
dc.language.isoengpt_PT
dc.publisherSPIE BiOSpt_PT
dc.relationProject nr. 662 - FCT program Research4COVID 19pt_PT
dc.relationPhotonic biosensor for point of care and early diagnostics of acute kidney injury
dc.relationEgas Moniz Interdisciplinary Research Center
dc.relationApplied Molecular Biosciences Unit
dc.relationUID/EEA/00066/2020 - ERDF under the PT2020 Partnership Agreementpt_PT
dc.relationProjeto financiado no âmbito do Concurso de Projetos de Investigação, Desenvolvimento, Inovação & Criação Artística (IDI&CA) financiados pelo Instituto Politécnico de Lisboa. IPL/2020/AGE-SPReS/ISELpt_PT
dc.relationLISBOA-01-0145-FEDER-031311 - FEDER European Regional Development Fund
dc.subjectGreen gold nanoparticlespt_PT
dc.subjectPlasmonic bandpt_PT
dc.subjectNanoparticles immobilizationpt_PT
dc.subjectITOpt_PT
dc.titleGreen synthesis of gold nanoparticles and their deposition on ITO surfacespt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitlePhotonic biosensor for point of care and early diagnostics of acute kidney injury
oaire.awardTitleEgas Moniz Interdisciplinary Research Center
oaire.awardTitleApplied Molecular Biosciences Unit
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC%2FNAN-OPT%2F31311%2F2017/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04585%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FMulti%2F04378%2F2013/PT
oaire.citation.endPage116590Q-9pt_PT
oaire.citation.startPage116590Q-1pt_PT
oaire.citation.titleColloidal Nanoparticles for Biomedical Applications XVIpt_PT
oaire.citation.volume11659pt_PT
oaire.fundingStream9471 - RIDTI
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
person.familyNameFantoni
person.familyNameRuas da Trindade Maçarico
person.familyNameAlegria
person.givenNameAlessandro
person.givenNameAntónio Filipe
person.givenNameElisabete
person.identifier863202
person.identifier.ciencia-id241E-E87C-552F
person.identifier.ciencia-idE018-BC2E-29CD
person.identifier.ciencia-id8C1F-851A-9F1C
person.identifier.orcid0000-0002-9938-0351
person.identifier.orcid0000-0001-6213-925X
person.identifier.orcid0000-0003-4060-1057
person.identifier.ridK-1105-2016
person.identifier.ridE-9945-2012
person.identifier.scopus-author-id7006535604
person.identifier.scopus-author-id8315848300
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsclosedAccesspt_PT
rcaap.typeconferenceObjectpt_PT
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