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Multichannel detector system for surface plasmon resonance biosensors

2022-03-07Conference object Restricted access
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dc.contributor.authorFernandes, Miguel
dc.contributor.authorFantoni, Alessandro
dc.contributor.authorSoares, Paulo
dc.contributor.authorLourenço, Paulo
dc.contributor.authorVieira, Manuela
dc.date.accessioned2022-03-09T10:39:08Z
dc.date.available2022-03-09T10:39:08Z
dc.date.issued2022-03-07
dc.descriptionEste trabalho foi financiado pelo Concurso Anual para Projetos de Investigação, Desenvolvimento, Inovação e Criação Artística (IDI&CA) 2020 do Instituto Politécnico de Lisboa. Código de referência IPL/2020/AGE-SPReS/ISEL
dc.description.abstractPhotonic systems are gaining an important role in the field of medical diagnosis due to the achievable high sensitivity and selectivity and low cost, enabling the fabrication of disposable point of care diagnosis systems for multiple pathologies. In this work we present the detector subsystem developed for a multi-channel surface plasmon resonance (SPR) based sensor. The core of the system is a multimode interferometer splitter, fabricated in amorphous silicon, followed by multiple sensitive SPR structures with a functionalized gold layer that modulate the transmitted light waves, in the presence of the biomarker, which are then detected by infrared detectors. For this purpose a highly adaptable detection system based on a InGaAs line CCD device was developed. The IR sensor used in the prototype has 128 (50 x 250 μm) pixels but other formats are supported. To adapt to different light guiding structures, the CCD pixels can be combined forming multiple detection channels. Optical sensor configuration and readout operations are performed trough a USB connection using the SCPI standard. The system includes an analog front end with a programmable gain amplifier and offset adjustment followed by a fast analog to digital converter feeding the data to a STM32 family processor. A computer application was also developed for system configuration and signal readout and storage. The testing results from the complete system are presented. Documentation of the developed system is provided for third party use, all the material generated within this work is available online in a repository.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFERNANDES, Miguel; [et al] – Multichannel detector system for surface plasmon resonance biosensors. In Proceedings of SPIE 11953, Optical Fibers and Sensors for Medical Diagnostics, Treatment and Environmental Applications XXII. San Francisco, California, United States (2 March 2022). ISSN 1605-7422. Vol. 11953. Pp. 119530J-1- 119530J-1.pt_PT
dc.identifier.doi10.1117/12.2610194pt_PT
dc.identifier.issn1605-7422
dc.identifier.urihttp://hdl.handle.net/10400.21/14417
dc.language.isoengpt_PT
dc.publisherSPIEpt_PT
dc.relationLISBOA-01-0145- FEDER-031311 - EU funds through the FEDER European Regional Development Fundpt_PT
dc.relationPTDC/NAN-OPT/31311/2017 - FCTpt_PT
dc.relationUID/EEA/00066/2020 - FCTpt_PT
dc.relationProjeto financiado no âmbito do Concurso de Projetos de Investigação, Desenvolvimento, Inovação & Criação Artística (IDI&CA) financiados pelo Instituto Politécnico de Lisboa. IPL/2020/AGE-SPReS/ISELpt_PT
dc.subjectSurface plasmon resonancept_PT
dc.subjectOptical bio sensorpt_PT
dc.subjectHAMAMATSU-G13913pt_PT
dc.subjectLinear image sensorpt_PT
dc.titleMultichannel detector system for surface plasmon resonance biosensorspt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceSan Francisco, California, United Statespt_PT
oaire.citation.endPage119530J-1pt_PT
oaire.citation.startPage119530J-1pt_PT
oaire.citation.titleOptical Fibers and Sensors for Medical Diagnostics, Treatment and Environmental Applications XXIIpt_PT
oaire.citation.volume11953pt_PT
person.familyNameFernandes
person.familyNameFantoni
person.familyNameLourenço
person.familyNameVieira
person.givenNameMiguel
person.givenNameAlessandro
person.givenNamePaulo
person.givenNameManuela
person.identifier10792
person.identifier.ciencia-idDD1B-859F-EB0B
person.identifier.ciencia-id241E-E87C-552F
person.identifier.ciencia-id431F-5C2C-00FB
person.identifier.ciencia-id9516-E25E-BB8E
person.identifier.orcid0000-0002-0765-474X
person.identifier.orcid0000-0002-9938-0351
person.identifier.orcid0000-0002-8785-445X
person.identifier.orcid0000-0002-1150-9895
person.identifier.ridK-1105-2016
person.identifier.ridV-7860-2017
person.identifier.scopus-author-id24450183800
person.identifier.scopus-author-id7006535604
person.identifier.scopus-author-id7202140173
rcaap.rightsclosedAccesspt_PT
rcaap.typeconferenceObjectpt_PT
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