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Effect of graphene vs. reduced graphene oxide in gold nanoparticles for optical biosensors: a comparative study

2022-03-04Journal article Open access
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dc.contributor.authorCarvalho, Ana P. G.
dc.contributor.authorAlegria, Elisabete
dc.contributor.authorFantoni, Alessandro
dc.contributor.authorFerraria, Ana Maria
dc.contributor.authorRego, Ana
dc.contributor.authorDa Costa Ribeiro, Ana Paula
dc.date.accessioned2022-03-09T12:14:42Z
dc.date.available2022-03-09T12:14:42Z
dc.date.issued2022-03-04
dc.description.abstractAiming to develop a nanoparticle-based optical biosensor using gold nanoparticles (AuNPs) synthesized using green methods and supported by carbon-based nanomaterials, we studied the role of carbon derivatives in promoting AuNPs localized surface plasmon resonance (LSPR), as well as their morphology, dispersion, and stability. Carbon derivatives are expected to work as immobilization platforms for AuNPs, improving their analytical performance. Gold nanoparticles (AuNPs) were prepared using an eco-friendly approach in a single step by reduction of HAuCl4·3H2O using phytochemicals (from tea) which act as both reducing and capping agents. UV–Vis spectroscopy, transmission electron microscopy (TEM), zeta potential (ζ-potential), and X-ray photoelectron spectroscopy (XPS) were used to characterize the AuNPs and nanocomposites. The addition of reduced graphene oxide (rGO) resulted in greater dispersion of AuNPs on the rGO surface compared with carbon-based nanomaterials used as a support. Differences in morphology due to the nature of the carbon support were observed and are discussed here. AuNPs/rGO seem to be the most promising candidates for the development of LSPR biosensors among the three composites we studied (AuNPs/G, AuNPs/GO, and AuNPs/rGO). Simulations based on the Mie scattering theory have been used to outline the effect of the phytochemicals on LSPR, showing that when the presence of the residuals is limited to the formation of a thin capping layer, the quality of the plasmonic resonance is not affected. A further discussion of the application framework is presented.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCARVALHO, Ana P. G.; [et al] – Effect of graphene vs. reduced graphene oxide in gold nanoparticles for optical biosensors – A comparative study. Biosensors. eISSN 2079-6374. Vol. 12, N.º 3 (2022), pp. 1-20.pt_PT
dc.identifier.doi10.3390/bios12030163pt_PT
dc.identifier.eissn2079-6374
dc.identifier.urihttp://hdl.handle.net/10400.21/14421
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relationLISBOA-02-0145-FEDER-031311 - EU funds through the FEDER European Regional Development Fundpt_PT
dc.relationPTDC/NAN-OPT/31311/2017 - FCTpt_PT
dc.relationPTDC/QUIQIN/29778/2017 - FCTpt_PT
dc.relationUIDB/00100/2020 - Centro de Química Estruturalpt_PT
dc.relationLA/P/0056/2020 - Institute of Molecular Sciencespt_PT
dc.relationUIDB/04565/2020 - iBBpt_PT
dc.relationLA/P/0140/2020 - i4HBpt_PT
dc.relationUID/EEA/00066/2020 - Center of Technology and Systemspt_PT
dc.relationIPL/2018/STREAM/ISELpt_PT
dc.relationIPL/2020/AGE-SPReS/ISELpt_PT
dc.relationIST-ID/119/2018 - ISTpt_PT
dc.relationIST-ID/131/2018 - ISTpt_PT
dc.relation.publisherversionhttps://www.mdpi.com/2079-6374/12/3/163/htmpt_PT
dc.subjectBiosensorspt_PT
dc.subjectAuNPspt_PT
dc.subjectMetal–graphene hybridpt_PT
dc.subjectSimulationspt_PT
dc.subjectMie theorypt_PT
dc.titleEffect of graphene vs. reduced graphene oxide in gold nanoparticles for optical biosensors: a comparative studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage20pt_PT
oaire.citation.issue3pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleBiosensorspt_PT
oaire.citation.volume12pt_PT
person.familyNameAlegria
person.familyNameFantoni
person.familyNameFerraria
person.familyNameRego
person.familyNameda Costa Ribeiro
person.givenNameElisabete
person.givenNameAlessandro
person.givenNameAna Maria
person.givenNameAna
person.givenNameAna Paula
person.identifier863202
person.identifier1336277
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person.identifier.ciencia-idE115-5C31-30F4
person.identifier.orcid0000-0003-4060-1057
person.identifier.orcid0000-0002-9938-0351
person.identifier.orcid0000-0002-6784-6540
person.identifier.orcid0000-0002-3131-4219
person.identifier.orcid0000-0003-4323-4328
person.identifier.ridE-9945-2012
person.identifier.ridK-1105-2016
person.identifier.ridD-9186-2015
person.identifier.ridL-4670-2013
person.identifier.ridF-8341-2014
person.identifier.scopus-author-id8315848300
person.identifier.scopus-author-id7006535604
person.identifier.scopus-author-id6508076737
person.identifier.scopus-author-id7003865928
person.identifier.scopus-author-id22235818800
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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