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BioMol4Health_Biological chemistry: longevity in a cup of tea

2018-10Conference object Open access
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dc.contributor.authorRESSAISSI, Asma
dc.contributor.authorFale, Pedro
dc.contributor.authorPacheco, Rita
dc.contributor.authorSerralheiro, Maria Luisa
dc.date.accessioned2020-03-26T19:31:29Z
dc.date.available2020-03-26T19:31:29Z
dc.date.issued2018-10
dc.description.abstractInfusions have been studied on what concerns Alzheimer Disease, digestive process, diet cholesterol absorption and its biosynthesis inhibition. In the first two cases the inhibition of acetylcholinesterase (AChE) has been addressed. In the last two situations, an in vitro intestinal barrier has been simulated and the inhibition of the regulator enzyme (HMGR) in cholesterol biosysnthesis pathway has been studied. AChE has been the target of infusions inhibitory activity as its inhibition has been seen to improve cognition and global functioning1 in AD suffering people and to improve the gastrointestinal motility2. Given to lab animals the compounds presente in the infusions were able to reach the brain and inhibit the enzyme3. The effect of infusions on cholesterol bioavailability pointed out that some infusions were able to reduce cholesterol permeation4 and also to have some inhibitory activity5. Studies have indicated that phenolics are able to modify the cell proteome6. The infusions have also been shown to modify the amount of cholesterol transporter proteins in cell membrane and this maybe one of possible explanations for the reduction in cholesterol transport detected under the effect of infusions, on some people ando n simulated intestinal barrier.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationRESSAISSI, Asma; [et al] – BioMol4Health_Biological Chemistry: Longevity in a cup of tea. In Proceedings of Biomedical Biopharmaceutical Research. Lisboa, Portugal: ALIES - Associação Lusófona para o Desenvolvimento da Investigação e do Ensino das Ciências da Saúde, 2018. ISSN 2182-2379. Vol. 15, N.º 2, p. 266pt_PT
dc.identifier.doi10.19277/bbr.15.2.192.pt_PT
dc.identifier.issn2182-2379
dc.identifier.issn2182-2360
dc.identifier.urihttp://hdl.handle.net/10400.21/11351
dc.language.isoengpt_PT
dc.publisherALIES - Associação Lusófona para o Desenvolvimento da Investigação e do Ensino das Ciências da Saúdept_PT
dc.relationPEst-UID/AMB/50017/2013pt_PT
dc.subjectAcetylcholinesterasept_PT
dc.subjectCholesterolpt_PT
dc.subjectInfusionspt_PT
dc.subjectPhenolicspt_PT
dc.subjectIntestinal barrierpt_PT
dc.subjectCholesterol-transporter proteinspt_PT
dc.titleBioMol4Health_Biological chemistry: longevity in a cup of teapt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/PEst-OE%2FQUI%2FUI0612%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FMulti%2F00612%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FMulti%2F04046%2F2013/PT
oaire.citation.conferencePlace26 de Outubro de 2018 - Lisboa, Portugalpt_PT
oaire.citation.issue2pt_PT
oaire.citation.startPage266pt_PT
oaire.citation.titleProceedings of Biomedical Biopharmaceutical Researchpt_PT
oaire.citation.volume15pt_PT
oaire.fundingStream3599-PPCDT
oaire.fundingStream5876
oaire.fundingStream5876
person.familyNameRESSAISSI
person.familyNameFale
person.familyNamePacheco
person.familyNameSerralheiro
person.givenNameAsma
person.givenNamePedro
person.givenNameRita
person.givenNameMaria Luisa
person.identifier1022927
person.identifier.ciencia-id9F13-D310-B5A3
person.identifier.orcid0000-0002-0073-6785
person.identifier.orcid0000-0002-4644-7655
person.identifier.orcid0000-0001-5192-3006
person.identifier.orcid0000-0001-7541-9613
person.identifier.ridA-5570-2013
person.identifier.ridC-3062-2012
person.identifier.ridE-3407-2012
person.identifier.scopus-author-id25649775000
person.identifier.scopus-author-id8853708300
person.identifier.scopus-author-id6602688573
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
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