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- An optimization strategy for customized radiotherapy head immobilization masksPublication . Craveiro, D.S.; Loja, Amélia; Vieira, Lina Oliveira; Vinyas, M.An effective head immobilization is an important requirement in radiotherapy treatment sessions, although it may also be thought in the future as a precious aid in brain medical imaging. Thus, the present work is focused on the stiffness optimization of a customized head immobilization mask, modelled upon the head reconstruction surface based on computerized tomography images. This paper proposes a strategy supported by a metaheuristic optimization technique and a metamodeling approach for the whole mask, illustrated at its most unfavorable region occurring in the gnathion region.