Loading...
2 results
Search Results
Now showing 1 - 2 of 2
- Impact of supraphysiological doses of anabolic steroids on glucose and insulin levels in male bodybuilders: a systematic reviewPublication . Tavares, Ana Sofia; Bellém, Fernando; Ferreira, Bárbara; Leite, Beatriz; Calixto, CarolinaTestosterone (TE) is an anabolic androgenic steroid (AAS) that promotes muscle growth and the maintenance of secondary sexual characteristics. Due to its aesthetic benefits, AASs have become popular in sports, typically administered orally or intramuscularly, with doses up to 100 times higher than the therapeutic dose. A therapeutic dose is safe and sufficient for the desired effect, while a supraphysiological dose is significantly greater than what is needed for normal body functions. Insulin regulates blood glucose levels and metabolic processes. Insulin resistance occurs when cells do not respond well to this hormone, leading to elevated blood sugar levels. It is believed that TE disrupts the secretion of adipocytokines, increases the amount of circulating fatty acids, and may negatively affect insulin signaling in muscle and fat cells. This systematic review aims to understand the influence of administering supraphysiological doses of AASs on blood glucose and insulin levels in male bodybuilding athletes.
- Impact of non-therapeutic doses of anabolic steroids on glucose and insulin levels in male bodybuilders: systematic reviewPublication . Tavares, Ana Sofia; Ferreira, Bárbara; Leite, Beatriz; Calixto, Carolina; Bellém, FernandoBackground: Anabolic androgenic steroids (AAS) are synthetic compounds with a chemical structure similar to testosterone. Bodybuilders frequently use them to increase muscle mass, and strength, and reduce body fat. However, AAS can also have adverse effects on health, including alterations in glucose and insulin levels. Aims: This systematic literature review aimed to collect and critically analyze studies that describe the impact of AAS use, in non-therapeutic doses, on glucose and insulin levels in male bodybuilders. Method: The PRISMA guidelines were followed, and four articles were included using electronic databases such as PubMed, Scopus, and Web of Science. Results: The analyzed studies present results of insulin and glucose measurements in an interventional group and a control group, showing that AAS can influence these levels. AAS may decrease insulin sensitivity, which can increase the risk of developing type 2 diabetes. Conclusion: Bodybuilders AAS´s users should have professional counseling about the negative health impact of these substances and be subject to regular check-ups to check their health status.