Browsing by Author "Neuparth, Nuno"
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- Classificação GOLD e sintomas respiratórios em idosos: estudo GERIAPublication . Palmeiro, Teresa; Belo, Joana; Caires, Iolanda; Sousa, Rui; Monteiro, Diogo; Botelho, Amália; Martins, Pedro; Neuparth, NunoA Europa assiste ao envelhecimento da população, onde a doença respiratória assume relevância. Com o aumento da idade, da exposição à poluição ambiental e do tabagismo, a prevalência da Doença Pulmonar Obstrutiva Crónica (DPOC) tende a ser elevada, nomeadamente na população idosa. A idade avançada poderá associar-se com uma menor percepção de sintomas, pelo que a espirometria será útil nesta faixa etária. Objetivo do estudo - Descrever o resultado da espirometria com prova de broncodilatação, de acordo com os critérios GOLD e prevalência de sintomas respiratórios dos idosos residentes num lar de Lisboa.
- Colaboração na realização da espirometria numa população de idosos: estudo GERIAPublication . Caires, Iolanda; Belo, Joana; Palmeiro, Teresa; Sousa, Rui; Monteiro, Diogo; Botelho, Amália; Martins, Pedro; Neuparth, NunoA espirometria é o método de eleição para a identificação de alterações ventilatórias, porém é pouco utilizada em idosos pelo fato de habitualmente se considerar que estes não conseguem colaborar. Este estudo tem como objetivo avaliar a colaboração na realização da espirometria antes e após administração de broncodilatador numa população de idosos residente num lar de Lisboa.
- Perfil espirométrico e sintomas respiratórios numa amostra de idosos sem história de doença respiratória: estudo GERIAPublication . Belo, Joana; Palmeiro, Teresa; Caires, Iolanda; Sousa, Rui; Monteiro, Diogo; Botelho, Amália; Martins, Pedro; Neuparth, NunoO sistema respiratório sofre alterações inerentes ao envelhecimento que, aliadas à exposição ambiental e à carga tabágica contribuem para um maior declínio da função respiratória. Os testes de função respiratória (e.g. espirometria) contribuem para uma melhor identificação alterações ventilatórias nas vias aéreas, tendo em conta que idade avançada poderá ser um fator para má perceção de sintomas. Objetivo do estudo - Caracterizar o perfil espirométrico e os sintomas respiratórios em idosos sem história de doença respiratória, residentes num lar de Lisboa.
- Reference values for spirometry in elderly individuals: a cross-sectional study of different reference equationsPublication . Belo, Joana; Palmeiro, Teresa; Caires, Iolanda; Papoila, Ana L.; Alves, Marta; Carreiro-Martins, Pedro; Botelho, Maria A.; Neuparth, NunoBackground: Spirometry is the single most important test for the evaluation of the respiratory function. The results are interpreted by comparing measured data with predicted values previously obtained from a reference population. Reference equations for spirometry have been discussed previously. The aim of this study was to compare reference values based on National Health and Nutrition Assessment Survey (NHANES III), European Community of Steel and Coal (ECSC), and Global Lung Initiative (GLI) equations in an elderly sample population. Methods: Subjects from the Geriatric Study on Health Effects of Air Quality in elder care centers who met the inclusion criteria were enrolled. Spirometry was performed according to international guidelines. The forced vital capacity, forced expiratory volume in 1 s, and the FEV1/FVC ratio was reported as percentages of the predicted value, and the lower limit of normality was calculated. Results: Out of 260 elderly patients, 69.6% were women; the mean age was 83.0 ± 6.46 years with an age range of 65-95 years. The lowest %FVC and %FEV1 values were obtained using the GLI reference equations. However, when NHANES III equations were used, the FEV1/FVC ratio was higher than ratios obtained from GLI and ECSC equations. The prevalence of airway obstruction was highest using ECSC equations, while GLI equations demonstrated more restrictive defects. Conclusions: The present study showed meaningful differences in the reference values, and consequently, in the results obtained using NHANES III, ECSC, and GLI reference equations. The spirometry interpretation was also influenced by the reference equations used.
- The impact of indoor air quality on respiratory health of older people living in nursing homes: spirometric and exhaled breath condensate assessmentsPublication . Belo, Joana; Carreiro-Martins, Pedro; Papoila, Ana L.; Palmeiro, Teresa; Caires, Iolanda; Alves, Marta; Nogueira, Susana; Aguiar, Fátima; Mendes, Ana; Cano, Manuela; Botelho, Maria A.; Neuparth, NunoIn the Portuguese Geriatric Study of the Health Effects of Indoor Air Quality in Senior Nursing Homes, we aimed to evaluate the impact of indoor air contaminants on the respiratory symptoms and biomarkers in a sample of elderly living in nursing homes. A total of 269 elderly answered a health questionnaire, performed spirometry and 150 out of these collected an exhaled breath condensate sample for pH and nitrites analysis. The study included the evaluation of indoor chemical and microbiological contaminants. The median age of the participants was 84 (78-87) years and 70.6% were women. The spirometric data indicated the presence of airway obstruction in 14.5% of the sample. Median concentrations of air pollutants did not exceed the existing standards, although increased peak values were observed. In the multivariable analysis, each increment of 100 µg/m3 of total volatile organic compounds was associated with the odds of respiratory infection in the previous three months ( OR̂ =1.05; 95% CI: 1.00-1.09). PM2.5 concentrations were inversely associated with pH values ( β̂ = -0.04, 95%: -0.06 to -0.01, for each increment of 10 µg/m3). Additionally, a direct and inverse association were found between total bacteria and FEV1/FVC and FVC, respectively.
- The impact of indoor air quality on respiratory health of older people: spirometric and exhaled breath condensate assessmentsPublication . Belo, Joana; Carreiro-Martins, Pedro; Papoila, Ana L.; Palmeiro, Teresa; Caires, Iolanda; Alves, Marta; Nogueira, Susana; Aguiar, Fátima; Mendes, Ana; Cano, Manuela; Botelho, Maria A.; Neuparth, NunoIn general, seven million deads are dur to the indoor and outdoor environment exposure. The elderly are identified as the one of the principal risk groups: the progressive decline of biological functions; cumulative environmental exposure; 90% of the time is in indoor spaces. The main goal of this study was to describe the impact of environmental exposure from the point of view of IAQ in respiratory health in a sample of elderly people living in nursing homes. The elderly were evaluated through spirometry and exhaled breath condensate (EBC).
- The potential role of peak nasal inspiratory flow to evaluate active sinonasal inflammation and disease severityPublication . Araújo-Martins, José; Brás-Geraldes, Carlos; Neuparth, NunoAlthough the pathophysiology of nasal polyposis is incompletely understood, rhinologists have seldom studied it with rhinomanometry or peak nasal inspiratory flow (PNIF) due to technical limitations and the perception that polyp size might impair reproducibility and the usefulness of recordings. The objective of this study is to assess how measures of rhinomanometry and PNIF relate to disease activity. Nineteen patients with polyps, 15 patients with chronic sinusitis without polyps and 11 negative controls were evaluated with active anterior rhinomanometry and PNIF. Sinusitis and polyp patients were re-evaluated after medical treatment. Polyp patients had the highest median Lund-Mackay score (14) and a median Johansen score of 1. PNIF and its variation after treatment were also lowest in this group (median 90 L/min before and after treatment; median variation of 0 L/min). Nasal resistance was similar between groups, and only correlated with Johansen score (Spearman=0.517, p=0.048) after treatment. Our study suggests that evaluating polyp patients using rhinomanometry and PNIF may provide useful and reproducible data. Several findings considered together suggest that polyp size is not the main determinant of nasal functional changes in these patients, warranting further studies to verify whether PNIF changes reflect sinus inflammation or merely airway obstruction.