Browsing by Author "Coelho, Carina Marques"
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- Análise da qualidade de vida em mulheres com cancro de mama submetidas a radioterapiaPublication . Calhelhas, Ana; Canto, Carlota; Gamboa, Maria; Monsanto, Fátima; Sá, Ana Cravo; Coelho, Carina Marques; Carolino, ElisabeteObjetivos do estudo - Analisar a qualidade de vida (QdV) de doentes com cancro de mama no final do tratamento de radioterapia.
- Avaliação de planeamentos dosimétricos em doentes submetidas a braquiterapia ginecológica: uma revisão da literaturaPublication . Coelho, Carina Marques; Vale, Alexandra; Figueiredo, Ana; Braz, Ana; Esteves, Joana; Sá, Ana Cravo; Monsanto, FátimaObjetivo do estudo - Pretende-se analisar os diferentes parâmetros de avaliação dos planeamentos dosimétricos de doentes com tumores do colo do útero, tratadas com braquiterapia ginecológica de alta taxa de dose, nomeadamente a dose administrada no volume alvo e nos órgãos de risco (OR). Pretende-se ainda analisar a concordância dos dados obtidos com as recomendações da GEC-ESTRO.
- Avaliação do efeito Tongue and Groove em IMRTPublication . Monsanto, Fátima; Barateiro, Andreia; Coelho, Carina Marques; Sá, Ana Cravo; Souto, Carmen; Faria, JorgeCom este estudo pretende-se avaliar, através de dosimetria fotográfica e com a ajuda do software RIT v5.1, a existência do efeito de Tongue and Groove em IMRT e quantificá-lo.
- Avaliação dosimétrica em tumores de mama: comparação de três técnicasPublication . Marques, João; Bressan, Stephania; Mamboury, Nicholas; Sá, Ana Cravo; Coelho, Carina Marques; Monsanto, FátimaObjetivo – Comparar a técnica convencional, a técnica de energias mistas e a técnica field-in-field com energias mistas, verificando a dose recebida nos órgãos de risco e no volume alvo. Metodologia – Quinze doentes com carcinoma da mama esquerda classificadas de T1-T3N0M0 foram tratadas com cirurgia conservadora da mama, seguida de radioterapia pós-operatória. Para cada doente realizaram-se 3 planeamentos dosimétricos, sendo que cada um deles diz respeito a uma das diferentes técnicas em estudo. Através dos HDV gerados avaliaram-se a Dmáx, Dmed, Dmín, D95%, D3% e a homogeneidade da dose no volume alvo, bem como a dose nos órgãos de risco. Utilizou-se o teste de Friedman para verificar a significância do estudo, com um intervalo de confiança de 95%. Resultados – Relativamente ao pulmão esquerdo e ao coração obtiveram-se, com a técnica field-in-field com energias mistas, doses inferiores em comparação com as outras duas técnicas. Para a Dmáx e a homogeneidade de dose no PTV, a técnica field-in-field com energias mistas revelou-se mais eficaz, comparativamente às outras técnicas. No entanto, verificou-se uma melhor cobertura de dose no PTV com a técnica convencional. Considerações finais – A técnica field-in-field com energias mistas permite uma redução da dose nos órgãos de risco, uma redução significativa da Dmáx no PTV e melhora a homogeneidade da dose, comparativamente com as outras técnicas. Os resultados obtidos com a técnica field-in-field com energias mistas apontam para a redução dos efeitos secundários provocados pelo tratamento. ABSTRACT - Purpose – To compare the conventional technique, the technique of mixed energies and the technique field-in-field with mixed energies, checking the received dose in organs at risk and target volume. Methods – Fifteen patients with carcinoma of the left breast classified as T1-T3N0M0 were treated with breast-conserving surgery, followed by postoperative radiotherapy. For each patient were carried out three dosimetric plannings, each one of them concerns the different techniques under study. Through the DVH generated to evaluate Dmax, Dmed, Dmin, D95%, D3% and the homogeneity of the target volume dose, well as the dose in organs at risk. We used the Friedman test to assess the significance of the study, with a confidence interval of 95%. Results – For the left lung and heart were obtained with the technique field-in-field with mixed energies, lower doses compared with the other two techniques. For the Dmax and the homogeneity of the PTV dose, the technique field-in-field with mixed energies was more effective compared to other techniques. However, there was a better coverage of the PTV dose with conventional technique. Conclusions – The technique field-in-field with mixed energy allows a reduction in dose for organs at risk, a significant reduction Dmax in PTV and improves the homogeneity of the dose compared with other techniques. The results obtained with the technique field-in-field with mixed energy indicate to reduce the side effects caused by the treatment.
- Cancer incidence projections for Lisbon and Santarém districts: an aid to radiotherapy services planningPublication . Monsanto, Fátima; Carolino, Elisabete; Ramos, R.; Sá, Ana Cravo; Coelho, Carina MarquesWill the existing means in Radiotherapy respond to the needs of the potential user population in 2014 for Lisbon and Santarém districts? Number of treatment units? Number of Radiotherapy Technologists? Temporal variations of the dimension and age structure of the populations: Coastal areas/Interior areas, Urban areas/Rural areas. Temporal variations in the incidence of several types of cancer. Overall objectives: evaluate of the necessities of Radiotherapy for Lisbon and Santarém districts in 2014 and elaboration of proposals that aim the access/use for the potential user population.
- Comparação da dose calculada entre a tomoterapia helicoidal e a arcoterapia de intensidade modulada em glioblastomas multiformesPublication . Pires, Cidália; Carvalho, Filipa; Sá, Ana Cravo; Coelho, Carina Marques; Monsanto, Fátima; Sacco, Vincenzo; Pereira, DanielaObjetivo do estudo - Comparar a dose calculada nos órgãos de risco (OR’s) e no volume alvo de planeamento (PTV), entre a tomoterapia helicoidal (TH) e a arcoterapia de intensidade modulada (RapidArc®), em glioblastomas multiformes (GBM).
- Comparação do movimento respiratório adquirido com TC 4D e com o sistema Calypso em cancro de pulmão: estudo de casoPublication . Costa, Sónia Oliveira; Sá, Ana Cravo; Mateus, Dalila; Marques, João; Coelho, Carina Marques; Monsanto, FátimaObjetivo do estudo - Comparar as amplitudes respiratórias segundo os eixos x, y e z adquiridos com a tomografia computorizada (TC) 4D e o sistema Calypso® em cancro de pulmão.
- Comparação entre o pencil beam convolution algorithm e o analytical anisotropic algorithm em tumores de mamaPublication . Sá, Ana Cravo; Coelho, Carina Marques; Monsanto, FátimaObjectivo do estudo: comparar o desempenho dos algoritmos Pencil Beam Convolution (PBC) e do Analytical Anisotropic Algorithm (AAA) no planeamento do tratamento de tumores de mama com radioterapia conformacional a 3D.
- Comparison of inverse planning systems based on biological or physical factors: Pinnacle®, Corvus® and Monaco®Publication . Coelho, Carina Marques; Faustino, V.; Heliodoro, H.; Monsanto, Fátima; Sá, Ana Cravo; Varandas, C.Radiotherapy (RT) is one of the most important approaches in the treatment of cancer and its performance can be improved in three different ways: through the optimization of the dose distribution, by the use of different irradiation techniques or through the study of radiobiological initiatives. The first is purely physical because is related to the physical dose distributiuon. The others are purely radiobiological because they increase the differential effect between the tumour and the health tissues. The Treatment Planning Systems (TPS) are used in RT to create dose distributions with the purpose to maximize the tumoral control and minimize the complications in the healthy tissues. The inverse planning uses dose optimization techniques that satisfy the criteria specified by the user, regarding the target and the organs at risk (OAR’s). The dose optimization is possible through the analysis of dose-volume histograms (DVH) and with the use of computed tomography, magnetic resonance and other digital image techniques.
- Comparison of the pencil beam convolution algorithm and the analytical anisotropic algorithm in breast tumorsPublication . Sá, Ana Cravo; Coelho, Carina Marques; Monsanto, FátimaThe calculation of the dose is one of the key steps in radiotherapy planning1-5. This calculation should be as accurate as possible, and over the years it became feasible through the implementation of new algorithms to calculate the dose on the treatment planning systems applied in radiotherapy. When a breast tumour is irradiated, it is fundamental a precise dose distribution to ensure the planning target volume (PTV) coverage and prevent skin complications. Some investigations, using breast cases, showed that the pencil beam convolution algorithm (PBC) overestimates the dose in the PTV and in the proximal region of the ipsilateral lung. However, underestimates the dose in the distal region of the ipsilateral lung, when compared with analytical anisotropic algorithm (AAA). With this study we aim to compare the performance in breast tumors of the PBC and AAA algorithms.