Browsing by Author "Baptista, Sara R."
Now showing 1 - 1 of 1
Results Per Page
Sort Options
- Synthesis of azobenzene dyes mediated by cotA laccasePublication . Sousa, Ana Catarina; Baptista, Sara R.; Martins, Lígia O.; Robalo, Maria PaulaAn eco-friendly protocol for the synthesis of azobenzene dyes by oxidative coupling of primary aromatic amines is reported. As efficient biocatalytic systems, CotA laccase and CotA laccase/ABTS (2,2’-azinobis(3-ethylbenzo-thiazoline-6-sulfonic acid)) enablethe oxidation of various substituted anilines, in aqueous medium, ambient atmosphere and under mild reaction conditions of pH and temperature. A series of azobenzene dyes were prepared in good to excellent yields in an one-potreaction. Amechanistic proposal for the formation of the azoderivatives is presented. Our strategy offers an alternative approach for the direct synthesis of azobenzene dyes, avoiding the harsh conditions generally required formost of the traditional synthetic methods.