Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.21/4884
Título: Human biomonitoring: biomarkers, susceptibility, and nutrigenetics
Autor: Ladeira, Carina
Palavras-chave: Formaldehyde
Human biomonitoring
Occupational health
Genotoxicity assessment
Antineoplastic drugs
Data: Jun-2015
Editora: Lambert Academic Publishing
Citação: Ladeira C. Human biomonitoring: biomarkers, susceptibility, and nutrigenetics. LAP Lambert Academic Publishing; 2015.
Resumo: The methods of molecular biology applied in epidemiological research lead us to the realm of molecular epidemiology, where there is immense potential for the establishment of associations between cancer and exposure to risk factors in lifestyle, profession, or pollution. Human biomonitoring consists, on the one hand, in research and identification of hazardous environmental conditions and, on the other hand, in the assessment of cancer risk following exposure to such conditions. Since carcinogenesis is a lengthy process, the biomarkers used to recognize biological abnormalities are selected and developed in the realm of molecular epidemiology. Such biomarkers are quantifiable and allow for the recognition of progression from normal to abnormal biological conditions at the molecular level. They can be categorized in biomarkers of exposure, effect, and genetic susceptibility. Genotoxicity biomarkers are a particular subset of effect biomarkers and are used to assess genomic instability caused by environmental or occupational exposure, being considered useful carcinogenesis predictors.
Peer review: yes
URI: http://hdl.handle.net/10400.21/4884
ISBN: 9783659689383
Versão do Editor: https://www.morebooks.de/store/gb/book/human-biomonitoring:-biomarkers,-susceptibility,-and-nutrigenetics/isbn/978-3-659-68938-3
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