Frija, LuísAlegria, ElisabeteSutradhar, ManasCristiano, Maria De LurdesIsmael, AminKopylovich, MaximilianPombeiro, Armando2017-01-172017-01-172016-12-15FRIJA, Luís M.T.; [et al] – Copper(II) and cobalt(II) tetrazole-saccharinate complexes as effective catalysts for oxidation of secondary alcohols. Journal of Molecular Catalysis A: Chemical. ISSN 1381-1169. Vol. 425 (2016), pp. 283–290.1381-1169http://hdl.handle.net/10400.21/6733Mononuclear Cu(II) and Co(II) complexes comprising 2-methyltetrazole-saccharinate bidentate N,N-chelating ligand have been synthesized for the first time and tested as homogeneous catalysts for oxidation of secondary alcohols in a solvent-free and microwave assisted protocol using aqueous tert-butyl hydroperoxide (TBHP) as oxidant. The developed catalytic system exhibits broad functional group compatibility, allowing efficient and selective conversion of a variety of secondary alcohols, including allylic ones, into the corresponding ketones. With typical 0.2 mol% content of the catalyst and under 20–50 W microwave irradiation, most reactions are complete within 10 min, presenting TONs up to 5.5 × 102 and TOFs up to 1.1 × 104 h−1. No additives and co-oxidants have been used, while TEMPO (2,2,6,6-tetramethyl-1-piperidinyloxyl) acts as inhibitor in most cases. A plausible reaction mechanism involving the new catalytic systems is outlined.engCu(II) and Co(II) catalystsTetrazole-saccharinate ligandsSecondary alcoholsAlcohol oxidationMicrowave irradiationjournal articlehttp://dx.doi.org/10.1016/j.molcata.2016.10.023