Veiga, JoaquimCarmona, BrunoCamelo, CarolinaPereira, DulceMarinho, H. SusanaSoares, Helena2017-07-242017-07-242017-05Veiga J, Carmona B, Camelo C, Pereira D, Marinho HS, Soares H. TBCCD1 and OFD1, a novel centrosomal protein partnership with a role in human ciliopathies?. In CQB day 2017, FCUL, May 31st 2017.http://hdl.handle.net/10400.21/7303Este trabalho foi financiado pelo Concurso Anual para Projetos de Investigação, Desenvolvimento, Inovação e Criação Artística (IDI&CA) 2016 do Instituto Politécnico de Lisboa. Código de referência: IPL/2016/TBCCentro_ESTeSLCilia are hair-like appendages, consisting of a microtubule (MT)-based ciliary axoneme, that fulfill critical motility and sensory functions required for normal embryonic development and also for homeostasis of adult tissues. At their base, cilia have a centriole/basal body, which can be derived from the centrosome, and that nucleates the ciliary axoneme (primary cilia). Centrosomes consist of a pair of centrioles surrounded by the pericentriolar matrix that nucleate/organize the cytoskeleton and are implicated in cell migration, adhesion and polarity, while in mitosis they assist spindle pole formation.engTBCCD1OFD1Human ciliopathiesIPL/2016/TBCCentro_ESTeSLconference object