Zhou, ZheminAlikhan, Nabil-FareedSergeant, MartinLuhmann, NinaVaz, CátiaFrancisco, AlexandreCarrico, JoaoAchtman, Mark2018-11-282018-11-282018-09ZHEMIN, Zhou; [et al] – GrapeTree visualization of core genomic relationships among 100,000 bacterial pathogens. Genome Research. ISSN 1088-9051. Vol. 28, N.º 9 (2018), pp. 1395-14041088-90511549-5469http://hdl.handle.net/10400.21/9099Current methods struggle to reconstruct and visualize the genomic relationships of large numbers of bacterial genomes. GrapeTree facilitates the analyses of large numbers of allelic profiles by a static "GrapeTree Layout" algorithm that supports interactive visualizations of large trees within a web browser window. GrapeTree also implements a novel minimum spanning tree algorithm (MSTree V2) to reconstruct genetic relationships despite high levels of missing data. GrapeTree is a stand-alone package for investigating phylogenetic trees plus associated metadata and is also integrated into EnteroBase to facilitate cutting edge navigation of genomic relationships among bacterial pathogens.engBacterial genomeGrapeTreeGenoma bacterianojournal article10.1101/gr.232397.117