Oliveira, KetlynAlmeida, AnaSilva, CarinaBrito, MiguelRibeiro, Edna2024-12-112024-12-112024-11Oliveira K, Almeida A, Silva C, Brito M, Ribeiro E. SARS-CoV-2 immunization index in the academic community: a retrospective post-vaccination study. Infect Dis Rep. 2024;16(6):1084-97.http://hdl.handle.net/10400.21/18006This work was supported by Project COVID management and acquired immunity assessment in the IPL community (COVIDVax_IPL) funded by Instituto Politécnico de Lisboa (IPL). H&TRC authors gratefully acknowledge the FCT/MCTES UIDP/05608/2020, and UIDB/05608/2020).Background/Objectives: The COVID-19 pandemic has revolutionized vaccine production and compelled a massive global vaccination campaign. This study aimed to estimate the positivity and levels of SARS-CoV-2 IgG antibodies acquired due to vaccination and infection in the academic population of a Portuguese university. Methods: Blood samples were collected and analyzed using the ELISA methodology, and statistical analysis was performed. Results: A total of 529 volunteers with at least one dose of the vaccine were enrolled in this study. Individuals without a prior COVID-19 diagnosis were divided into two groups: 350, who received a full vaccination, and 114, who received a full vaccination and a booster dose of the same vaccine (81) and mixed vaccines (33). Regarding the individuals who reported a prior SARS-CoV-2 infection, 31 received a full vaccination, and 34 received only one vaccination dose. Data analysis showed a higher level of IgG against SARS-CoV-2 in younger, female individuals who received the Moderna vaccine, with recent post-vaccine administration, a mixed booster dose, and prior SARS-CoV-2 infection. Conclusions: Assessing vaccination’s effectiveness and group immunity is crucial for pandemic management, particularly in academic environments with high individual mobility, to define groups at risk and redirect infection control strategies.engSARS-CoV-2ImmunityVaccinesAcademic communityImmunological variablesFCT_UIDP/05608/2020FCT_UIDB/05608/2020journal article10.3390/idr16060088