Da Costa Ribeiro, Ana PaulaAlegria, ElisabeteKopylovich, MaximilianFerraria, Ana MariaRego, AnaPombeiro, Armando2018-07-112020-07-012018-07-07RIBEIRO, Ana P. C.; [et al] – Comparison of microwave and mechanochemical energy inputs in the catalytic oxidation of cyclohexane. Dalton Transactions. ISSN 1477-9226. Vol. 47, N.º 25 (2018), pp. 8193-8198‎1477-92261477-9234http://hdl.handle.net/10400.21/8686Este trabalho foi financiado pelo Concurso Anual para Projetos de Investigação, Desenvolvimento, Inovação e Criação Artística (IDI&CA) 2016 do Instituto Politécnico de Lisboa. Código de referência IPL/2016/MechSynCat_ISELThe effect of microwave and mechanochemical ball milling energy inputs was studied for the peroxidative oxidation (with aqueous H2O2) of cyclohexane to cyclohexanol and cyclohexanone, over CoCl2 and/or V2O5 dispersed (μm scale) catalysts. A maximum total yield of cyclohexanol and cyclohexanone of 43% after 1 h of reaction at 30 °C, in acetonitrile and under microwave irradiation (5 W), was achieved over the CoCl2–V2O5 (3 : 1) catalyst prepared by ball milling. Cyclohexanol is the main final product with a selectivity of up to 93% over cyclohexanone. Conducting the oxidation reaction under microwave irradiation under the same conditions but without any mechanochemical treatment of the catalyst prior to use resulted in a lower total yield of 30% with a lower selectivity (69%) towards cyclohexanol over cyclohexanone. The sole application of mechanochemical treatment for the catalyst preparation and the catalytic oxidation of cyclohexane allowed to reach yields of 29% after 1 h of reaction, at room temperature, without microwave irradiation and any additive and in the absence of any organic solvent. Ball milling is shown to provide a convenient, solvent-free method to disperse these solid catalysts and to promote the above cyclohexane oxidation, although, in the latter case, not so effectively as microwave irradiation.engMicrowaveMechanochemicalCyclohexanejournal article10.1039/c8dt00866c