Brito, MiguelGinete, CatarinaMendes, ManuelaAfonso, RobertoSiatembo, AdrianoNeto-Vasconcelo, JocelyneInusa, Baba2025-12-232025-12-232025-12Brito M, Ginete C, Mendes M, Afonso R, Siatembo A, Neto-Vasconcelos J, et al. Newborn screening for sickle cell disease in a hospital setting in Luanda, Angola: local implementing learning from an international Consortium. In: 67th ASH Annual Meeting, New Orleans, Louisiana (USA), December 6-9, 2025.http://hdl.handle.net/10400.21/22398This study has been conducted within the African Research and Innovative Initiative for Sickle Cell Education (ARISE) that has received funding from the European Union's Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No 824021. This project also has the financial support of IPL/IDI&CA2024/GenFalci_ESTeSL and of FCT/MCTES H&TRC UIDB/05608/2020 and UIDP/05608/2020.Early diagnosis of Sickle Cell Disease (SCD) is critical to reducing mortality and morbidity in affected children; however, it remains largely unavailable in Sub-Saharan Africa, where disease prevalence is highest. This severe monogenic recessive disorder has an estimated mortality rate of 50–90% by age five if left undiagnosed. The Lancet Haematology Commission strongly recommends that all children worldwide be screened for SCD by 2025. This work aims to share the results from implementing newborn screening for Sickle Cell Disease at Hospital Materno-Infantil Dr. Manuel Pedro Anzacot de Menezes, Angola.engSickle cell diseaseNewborn screeningHospitalAngolaLuandaIPL/IDI&CA2024/GenFalci_ESTeSLFCT_UIDB/05608/2020FCT_UIDP/05608/2020Sickle cell traitClinical researchStudy populationEpidemiologyMolecular biologyHemoglobinopathyBiological processReal-world evidenceconference poster