Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.21/678
Título: Interaction of formaldehyde and tobacco smoking in the frequency of micronucleus and the XRCC3 Thr241Met polymorphism
Autor: Ladeira, Carina
Gomes, Manuel C.
Brito, Miguel
Palavras-chave: Anatomia patológica
Saúde ocupacional
Formaldeído
Tabagismo
Consumo de álcool
Factor de risco
Data: Set-2010
Citação: Ladeira C, Gomes MC, Brito M. Interaction of formaldehyde and tobacco smoking in the frequency of micronucleus and the XRCC3 Thr241Met polymorphism. In 8th International Symposium on Biological Monitoring in Occupational and Environmental Health, Finland, 6th September 2010. Oral presentation.
Resumo: Formaldehyde is classified by IARC as carcinogenic to humans (nasopharyngeal cancer). Tobacco smoke has been epidemiologically associated to a higher risk of development of cancer, especially in the oral cavity, larynx and lungs, as these are places of direct contact with many carcinogenic tobacco’s compounds. XRCC3 is involved in homologous recombination repair of cross-links and chromosomal double-strand breaks (Thr241Met polymorphism). The aim of the study is to determine whether there is an in vivo association between genetic polymorphism of the gene XRCC3 and the frequency of genotoxicity biomarkers in subjects exposed or not to formaldehyde and with or without tobacco consumption.
Peer review: yes
URI: http://hdl.handle.net/10400.21/678
Aparece nas colecções:ESTeSL - Comunicações

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